PLAU/uPA Protein, Mouse, Recombinant (His & Avi), Biotinylated

Catalog No. TMPK-00783

Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC. PLAU/uPA Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 49.00 kDa and the accession number is P06869.

PLAU/uPA Protein, Mouse, Recombinant (His & Avi), Biotinylated

Catalog No. TMPK-00783

Pack Size	Price	Availability
5 μg	$91	7-10 days
10 μg	$148	7-10 days
20 μg	$245	7-10 days
50 μg	$483	7-10 days
100 μg	$813	7-10 days
200 μg	$1,470	7-10 days
500 μg	$3,250	7-10 days

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Product Information

Biological Activity	Mouse uPAR isoform 1, His Tag immobilized on CM5 Chip can bind Biotinylated Mouse PLAU, His-Avi Tag with an affinity constant of 0.19 μM as determined in SPR assay.
Description	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC. PLAU/uPA Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 49.00 kDa and the accession number is P06869.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-His-Avi
Accession Number	P06869
Synonyms	Urokinase,URK,u-PA,UPA,QPD,PLAU,BDPLT5,ATF
Construction	Gly21-Phe433
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	49.00 kDa (predicted). Due to enzyme lysis and glycosylation, the protein migrates to 30-35 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.