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PF-6808472

🥰Excellent
Catalog No. T33955Cas No. 2088112-70-1
Alias PF6808472, PF 6808472, OX-44, OX44, OX 44

PF-6808472 is a cell permeable covalent probe suitable for click chemistry designated to measure kinase selectivity in intact cells. PF-6808472 contains sulfonyl fluoride group, which react with conserved lysine residue within kinase ATP binding site.

PF-6808472

PF-6808472

🥰Excellent
Purity: 99.02%
Catalog No. T33955Alias PF6808472, PF 6808472, OX-44, OX44, OX 44Cas No. 2088112-70-1
PF-6808472 is a cell permeable covalent probe suitable for click chemistry designated to measure kinase selectivity in intact cells. PF-6808472 contains sulfonyl fluoride group, which react with conserved lysine residue within kinase ATP binding site.
Pack SizePriceAvailabilityQuantity
1 mg$48In Stock
5 mg$113In Stock
10 mg$197In Stock
25 mg$455In Stock
50 mg$787In Stock
1 mL x 10 mM (in DMSO)$136In Stock
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Purity:99.02%
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Product Introduction

Bioactivity
Description
PF-6808472 is a cell permeable covalent probe suitable for click chemistry designated to measure kinase selectivity in intact cells. PF-6808472 contains sulfonyl fluoride group, which react with conserved lysine residue within kinase ATP binding site.
AliasPF6808472, PF 6808472, OX-44, OX44, OX 44
Chemical Properties
Molecular Weight538.6
FormulaC25H27FN8O3S
Cas No.2088112-70-1
SmilesN(C1=NC(=NC(C(NCC#C)=O)=C1)N2CCN(CC3=CC=C(S(F)(=O)=O)C=C3)CC2)C=4C=C(NN4)C5CC5
Relative Density.1.452 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55.48 mg/mL (103.01 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8567 mL9.2833 mL18.5667 mL92.8333 mL
5 mM0.3713 mL1.8567 mL3.7133 mL18.5667 mL
10 mM0.1857 mL0.9283 mL1.8567 mL9.2833 mL
20 mM0.0928 mL0.4642 mL0.9283 mL4.6417 mL
50 mM0.0371 mL0.1857 mL0.3713 mL1.8567 mL
100 mM0.0186 mL0.0928 mL0.1857 mL0.9283 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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