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Anti-Phospho-S6 Ribosomal Protein (Ser235, 236) Antibody (1E580)

(Synonyms: S6 Ribosomal Protein (p-Ser235, 236), S6 Ribosomal Protein (p-S235, 236), S6, p-S6 Ribosomal Protein (Ser235, 236), p-S6 Ribosomal Protein (S235, 236), Phospho-S6 Ribosomal Protein (S235, 236), OK/SW-cl.2, eS6) Copy Product Info
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Synonyms: S6 Ribosomal Protein (p-Ser235, 236), S6 Ribosomal Protein (p-S235, 236), S6, p-S6 Ribosomal Protein (Ser235, 236), p-S6 Ribosomal Protein (S235, 236), Phospho-S6 Ribosomal Protein (S235, 236), OK/SW-cl.2, eS6

Catalog No. TMAY-01581 Copy Product Info
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Anti-Phospho-S6 Ribosomal Protein (Ser235, 236) Antibody (1E580) is a Rabbit antibody targeting Phospho-S6 Ribosomal Protein (Ser235, 236). Anti-Phospho-S6 Ribosomal Protein (Ser235, 236) Antibody (1E580) can be used in WB.
Anti-Phospho-S6 Ribosomal Protein
(Ser235, 236) Antibody
(1E580)
Pack SizePriceUSA StockGlobal StockQuantity
20 μL$807-10 days7-10 days
100 μL$2337-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-S6 Ribosomal Protein (Ser235, 236) Antibody (1E580) is a Rabbit antibody targeting Phospho-S6 Ribosomal Protein (Ser235, 236). Anti-Phospho-S6 Ribosomal Protein (Ser235, 236) Antibody (1E580) can be used in WB.
SynonymsS6 Ribosomal Protein (p-Ser235, 236), S6 Ribosomal Protein (p-S235, 236), S6, p-S6 Ribosomal Protein (Ser235, 236), p-S6 Ribosomal Protein (S235, 236), Phospho-S6 Ribosomal Protein (S235, 236), OK/SW-cl.2, eS6
Ig Type
Rabbit IgG
Clone
1E580
Reactivity
Human;
Species predicted to react based on 100% sequence homology: mouse
Specificity
Human
Species predicted to react based on 100% sequence homology: mouse
Application
Recommended Dose
WB: 1:1000-1:5000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to residues around (Ser235, 236) of Human Phospho-S6 Ribosomal Protein.
PurificationProtein A
AppearanceLiquid
Formulation10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5
Research BackgroundRibosomal protein S6 (rpS6), a component of the 40S ribosomal subunit, is involved in multiple cellular bioactivities. RPS6 is a downstream substrate of PI3K/Akt/mTOR/ kinase and MAPK kinase pathways and its dephosphorylation is also triggered by DNA double-strand breaks. The ribosomal protein S6 (RPS6) is a downstream component of the signaling mediated by the target of rapamycin (TOR) kinase that acts as a central regulator of the key metabolic processes, such as protein translation and ribosome biogenesis, in response to various environmental cues. mTORC1/rpS6 signaling complex promoted Sertoli blood-testis barrier (BTB) remodeling by perturbing Sertoli cell-cell adhesion site known as the basal ectoplasmic specialization (ES). mTORC1/rpS6 complex also promoted disruption of spermatid adhesion at the Sertoli-spermatid interface called the apical ES.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide corresponding to residues around (Ser235, 236) of Human Phospho-S6 Ribosomal Protein
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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