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Ropivacaine

Name: Ropivacaine
Brand: TargetMol
SKU: T0386L
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0386LCas No. 84057-95-4

Alias LEA-103 HCl

Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.

Ropivacaine

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Purity: 99.86%

Catalog No. T0386LAlias LEA-103 HClCas No. 84057-95-4

Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.

Pack Size	Price	Availability
10 mg	$41	In Stock
25 mg	$58	In Stock
50 mg	$74	In Stock
100 mg	$97	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock

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Batch Information

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Purity:99.86%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.
Targets&IC50	TREK1 (COS-7 cell membrane):402.7 μM (IC50)
Synonyms	LEA-103 HCl

Chemical Properties

Molecular Weight	274.40
Formula	C₁₇H₂₆N₂O
Cas No.	84057-95-4
Smiles	CCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C
Relative Density.	1.044 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60.00 mg/mL (218.66 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6443 mL	18.2216 mL	36.4431 mL	182.2157 mL
5 mM	0.7289 mL	3.6443 mL	7.2886 mL	36.4431 mL
10 mM	0.3644 mL	1.8222 mL	3.6443 mL	18.2216 mL
20 mM	0.1822 mL	0.9111 mL	1.8222 mL	9.1108 mL
50 mM	0.0729 mL	0.3644 mL	0.7289 mL	3.6443 mL
100 mM	0.0364 mL	0.1822 mL	0.3644 mL	1.8222 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc