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Dapsone

Name: Dapsone
Brand: TargetMol
SKU: T0891
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T0891Cas No. 80-08-0

Alias Sulphadione, DDS, Bis(4-aminophenyl) sulfone, 4-Aminophenyl sulfone, 4,4'-Sulfonyldianiline, 4,4'-Diaminodiphenylsulfone

Dapsone (Sulphadione) has activity against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae.

Dapsone

🥰Excellent

Purity: 99.84%

Catalog No. T0891Alias Sulphadione, DDS, Bis(4-aminophenyl) sulfone, 4-Aminophenyl sulfone, 4,4'-Sulfonyldianiline, 4,4'-DiaminodiphenylsulfoneCas No. 80-08-0

Dapsone (Sulphadione) has activity against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae.

Pack Size	Price	Availability
1 g	$31	In Stock
5 g	$64	In Stock
10 g	$98	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.84%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Dapsone (Sulphadione) has activity against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae.
Synonyms	Sulphadione, DDS, Bis(4-aminophenyl) sulfone, 4-Aminophenyl sulfone, 4,4'-Sulfonyldianiline, 4,4'-Diaminodiphenylsulfone

Chemical Properties

Molecular Weight	248.30
Formula	C₁₂H₁₂N₂O₂S
Cas No.	80-08-0
Smiles	NC1=CC=C(C=C1)S(=O)(=O)C1=CC=C(N)C=C1
Relative Density.	1.2701 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 10.00 mg/mL (40.27 mM), Sonication is recommended.

DMSO: 50.00 mg/mL (201.37 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.0274 mL	20.1369 mL	40.2739 mL	201.3693 mL
5 mM	0.8055 mL	4.0274 mL	8.0548 mL	40.2739 mL
10 mM	0.4027 mL	2.0137 mL	4.0274 mL	20.1369 mL
20 mM	0.2014 mL	1.0068 mL	2.0137 mL	10.0685 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0805 mL	0.4027 mL	0.8055 mL	4.0274 mL
100 mM	0.0403 mL	0.2014 mL	0.4027 mL	2.0137 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc