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Anti-BTG2 Polyclonal Antibody
(Synonyms: TIS21, pheochromacytoma cell-3, PC3, NGF-inducible anti-proliferative protein PC3, nerve growth factor-inducible anti-proliferative, BTG2, BTG family member 2, B-cell translocation gene 2) Copy Product Info
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Synonyms: TIS21, pheochromacytoma cell-3, PC3, NGF-inducible anti-proliferative protein PC3, nerve growth factor-inducible anti-proliferative, BTG2, BTG family member 2, B-cell translocation gene 2
Catalog No. TMAB-00254 Copy Product Info
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Anti-BTG2 Polyclonal Antibody is a Rabbit antibody targeting CYP11A1. Anti-BTG2 Polyclonal Antibody can be used in WB.
Anti-BTG2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-BTG2 Polyclonal Antibody is a Rabbit antibody targeting CYP11A1. Anti-BTG2 Polyclonal Antibody can be used in WB. |
| Synonyms | TIS21, pheochromacytoma cell-3, PC3, NGF-inducible anti-proliferative protein PC3, nerve growth factor-inducible anti-proliferative, BTG2, BTG family member 2, B-cell translocation gene 2 |
| Ig Type | IgG |
| Reactivity | Human(predicted:Mouse,Rat,Pig,Rabbit,GuineaPig) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | BTG2 is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. BTG2 is involved in the regulation of the G1/S transition of the cell cycle. It modulates transcription regulation mediated by ESR1(referenced from Entrez Gene). BTG2 expression is induced in vivo during neurogenesis, and the gene is transiently expressed in vitro in rat pheochromocytoma PC12 cells after induction of neuronal differentiation by addition of nerve growth factor (NGF); suggesting that BTG2 is functionally significant during the neuronal differentiation process (PMID: 12360398). |
| Immunogen | KLH conjugated synthetic peptide: human BTG2 |
| Antigen Species | Human |
| Gene Name | BTG2 |
| Gene ID | |
| Protein Name | Protein BTG2 |
| Uniprot ID | |
| Biology Area | Other factors,Neurogenesis |
| Function | Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenyltion in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors. Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth. |
| Molecular Weight | Theoretical: 17 kDa. Actual: 17 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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