Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B16-F10 cells when used at lipid concentrations greater than 20 μM. DMHAPC-Chol, as part of a lipoplex with DOPE , has also been used to deliver DNA into mouse lung via intratracheal injection, resulting in a heterogeneous distribution in the bronchi and bronchioles, and to deliver VEGF siRNA into A431 and MDA-MB-231 cells, which secrete VEGF.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 78.00 | |
5 mg | 35 days | $ 273.00 | |
10 mg | 35 days | $ 460.00 | |
25 mg | 35 days | $ 1,050.00 |
Description | DMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B16-F10 cells when used at lipid concentrations greater than 20 μM. DMHAPC-Chol, as part of a lipoplex with DOPE , has also been used to deliver DNA into mouse lung via intratracheal injection, resulting in a heterogeneous distribution in the bronchi and bronchioles, and to deliver VEGF siRNA into A431 and MDA-MB-231 cells, which secrete VEGF. |
Molecular Weight | 559.89 |
Formula | C35H63N2O3 |
CAS No. | 794494-38-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 10 mg/mL
Ethanol: 10 mg/mL
Ethanol:PBS (pH 7.2) (1:6): 0.14 mg/mL
You can also refer to dose conversion for different animals. More
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DMHAPC-Chol 794494-38-5 DMHAPCChol DMHAPC Chol inhibitor inhibit