keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sotiburafusp alfa is a humanized bispecific fusion protein comprising a VEGFR-1 extracellular domain fragment (129-228, 1-100 in the current sequence) connected through a 101 GGSGGSGGSGGSGGS 115 peptide linker to the N-terminus (116-564) of a humanized IgG1-kappa anti-human PD-L1 heavy chain with L352<A and L353<A mutations. Additionally, sotiburafusp alfa functions as an angiogenesis inhibitor [1].
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Description | Sotiburafusp alfa is a humanized bispecific fusion protein comprising a VEGFR-1 extracellular domain fragment (129-228, 1-100 in the current sequence) connected through a 101 GGSGGSGGSGGSGGS 115 peptide linker to the N-terminus (116-564) of a humanized IgG1-kappa anti-human PD-L1 heavy chain with L352>A and L353>A mutations. Additionally, sotiburafusp alfa functions as an angiogenesis inhibitor [1]. |
Molecular Weight | N/A |
CAS No. | 2637466-37-4 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Sotiburafusp alfa 2637466-37-4 Angiogenesis Tyrosine Kinase/Adaptors VEGFR inhibitor inhibit