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interferon alpha 5/IFNA5 Protein, Human, Recombinant (His)
(Synonyms: RP11-380P16.5, leIF G, interferon-α, interferon, α5, interferon, alpha 5, INFA5, INA5, IFN-αG, IFN-α-5, IFN-α, IFN-alphaG, IFN-alpha-5, IFN-alpha) Copy Product InfoSynonyms: RP11-380P16.5, leIF G, interferon-α, interferon, α5, interferon, alpha 5, INFA5, INA5, IFN-αG, IFN-α-5, IFN-α, IFN-alphaG, IFN-alpha-5, IFN-alpha
Catalog No. TMPY-04855 Copy Product Info
interferon alpha 5/IFNA5 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 21.1 kDa and the accession number is A0A7R8C382.
| Pack Size | Price | EUR Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | 56 € | 7-10 days | 7-10 days | |
| 10 µg | 88 € | 7-10 days | 7-10 days | |
| 20 µg | 146 € | 7-10 days | 7-10 days | |
| 50 µg | 290 € | 7-10 days | 7-10 days | |
| 100 µg | 562 € | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: EUR Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Information
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Measured in antiviral assays using WISH cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is 0.8-8 pg/mL. |
| Description | interferon alpha 5/IFNA5 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 21.1 kDa and the accession number is A0A7R8C382. |
| Species | Human |
| Expression System | P. pastoris (Yeast) |
| Tag | C-His |
| Accession Number | P01569 |
| Construction | A DNA sequence encoding the human IFNA5 (NP_002160.1) (Leu22-Glu189) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Leu 22 |
| Protein Purity | > 90 % as determined by SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Synonyms | RP11-380P16.5, leIF G, interferon-α, interferon, α5, interferon, alpha 5, INFA5, INA5, IFN-αG, IFN-α-5, IFN-α, IFN-alphaG, IFN-alpha-5, IFN-alpha |
| Research Background | Interferon, alpha 5 (IFNA5) belongs to the alpha/beta interferon family. IFNA5 is the only IFNA subtype detected in normal liver, while a mixture of subtypes is observed in the liver tissue of patients with chronic hepatitis C. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytokine to be produced by recombinant DNA technology, has emerged as an important regulator of growth and differentiation, affecting cellular communication and signal transduction pathways as well as immunological control. Originally discovered as an antiviral substance, the efficacy of IFN-alpha in malignant, viral, immunological, angiogenic, inflammatory, and fibrotic diseases suggests a spectrum of interrelated pathophysiologies. IFN-alpha emerged as a prototypic tumor suppressor protein that represses the clinical tumorigenic phenotype in some malignancies capable of differentiation. |
| Molecular Weight | 21.1 kDa (predicted) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: interferon alpha 5/IFNA5 Protein, Human, Recombinant (His) chemical structure | interferon alpha 5/IFNA5 Protein, Human, Recombinant (His) molecular weight
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