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Anti-Netrin-1 Polyclonal Antibody

(Synonyms: Ntn1, Netrin-1) Copy Product Info
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Synonyms: Ntn1, Netrin-1

Catalog No. TMAB-01217 Copy Product Info
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Anti-Netrin-1 Polyclonal Antibody is a Rabbit antibody targeting Netrin-1. Anti-Netrin-1 Polyclonal Antibody can be used in ICC/IF, IF, IHC-Fr, IHC-P.
Anti-Netrin-1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Netrin-1 Polyclonal Antibody is a Rabbit antibody targeting Netrin-1. Anti-Netrin-1 Polyclonal Antibody can be used in ICC/IF, IF, IHC-Fr, IHC-P.
SynonymsNtn1, Netrin-1
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow)
Application
Recommended Dose
ICC/IF=1:100-500; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted, extracellular space, extracellular matrix.
Tissue SpecificityWidely expressed in normal adult tissues with highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundNetrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human NtN1
Antigen Species
Human
Gene Name
NTN1
Gene ID
Protein Name
Netrin-1
Uniprot ID
Biology Area
Axonal Guidance Proteins,Neurogenesis,Other ECM Proteins
Function
Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
Chemical Properties
Molecular WeightTheoretical: 64 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Related Tags: Anti-Netrin-1 Polyclonal Antibody molecular weight