Immunoglobulin lambda constant region is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. IGLC2 is 105 amino acids (aa) in length. It contains one Ig-like domain (aa 7-100) and generates a disulfide bond with an IgH chain via Cys104.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 118.00 | |
50 μg | 5 days | $ 355.00 | |
500 μg | 5 days | $ 2,010.00 | |
1 mg | 5 days | $ 3,020.00 |
Description | Immunoglobulin lambda constant region is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. IGLC2 is 105 amino acids (aa) in length. It contains one Ig-like domain (aa 7-100) and generates a disulfide bond with an IgH chain via Cys104. |
Species | Human |
Expression System | Human Cells |
Tag | C-6His |
Accession Number | P0DOY2 |
Synonyms | Ig λ constant 2 Protein, Human, Recombinant (His), MGC45681, IGLC, Ig Lambda C Domain, Ig λ C Domain, immunoglobulin lambda constant 2 (Kern-Oz- marker), MGC20392, immunoglobulin λ constant 2 (Kern-Oz- marker), IGLC2 |
Amino Acid | Gly1-Ser106 |
Construction | Recombinant Human Immunoglobulin Lambda Constant 2 is produced by our Mammalian expression system and the target gene encoding Gly1-Ser106 is expressed with a 6His tag at the C-terminus. |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 16 KDa, reducing conditions |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Stability & Storage |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Shipping |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Research Background | Immunoglobulin lambda constant region is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. IGLC2 is 105 amino acids (aa) in length. It contains one Ig-like domain (aa 7-100) and generates a disulfide bond with an IgH chain via Cys104. |
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Please read the User Guide of Recombinant Proteins for more specific information.
Ig lambda constant 2 Protein, Human, Recombinant (His) Ig λ constant 2 Protein, Human, Recombinant (His) IGLC-2 immunoglobulin lambda constant 2 MGC45681 Kern-Oz- marker MGC 20392 IGLC MGC-20392 MGC 45681 Ig Lambda C Domain Ig λ C Domain IGLC 2 immunoglobulin lambda constant 2 (Kern-Oz- marker) MGC-45681 MGC20392 immunoglobulin λ constant 2 (Kern-Oz- marker) IGLC2 recombinant recombinant-proteins proteins protein