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Anti-LAMP2 Antibody-PE (9Z568) is a PE-conjugated Rabbit antibody targeting LAMP2. Anti-LAMP2 Antibody-PE (9Z568) can be used in FCM.
Description | Anti-LAMP2 Antibody-PE (9Z568) is a PE-conjugated Rabbit antibody targeting LAMP2. Anti-LAMP2 Antibody-PE (9Z568) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 9Z568 |
Reactivity | Mouse |
Verified Activity | Flow cytometric analysis of Mouse LAMP2(CD107b) expression on BABL/c splenocytes. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with PE-conjugated anti-Mouse LAMP2(CD107b). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse LAMP2/CD107b (rM LAMP2/CD107b; TMPY-02382; P17047-1; Leu26-Asn379) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
Research Background | LAMP2 (Lysosomal Associated Membrane Protein 2) is a Protein Coding gene. LAMP2, also known as CD107b (Cluster of Differentiation 107b), is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. In humans, LAMP2, the causative gene of Danon disease, located on chromosome Xq24, encodes the lysosome-associated membrane protein-2 (LAMP-2). LAMP-2 deficiency, or Danon disease, is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. LAMP2 cardiomyopathy is an X-linked and highly progressive myocardial storage disorder associated with diminished survival, which clinically resembles sarcomeric hypertrophic cardiomyopathy. |
Conjucates | PE |
Others Formats | Unconjugated/FITC |
Antibody Types Available | 3 |
Immunogen | Recombinant Mouse LAMP2/CD107b Protein (TMPY-02382) |
Antigen Species | Mouse |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
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