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Anti-Thioredoxin 2/TRX2 Antibody (7F674)
🥰Excellent
Catalog No. TMAY-02379
Anti-Thioredoxin 2/TRX2 Antibody (7F674) is a Rabbit antibody targeting Thioredoxin 2/TRX2. Anti-Thioredoxin 2/TRX2 Antibody (7F674) can be used in IHC-P.
Anti-Thioredoxin 2/TRX2 Antibody (7F674)
Anti-Thioredoxin 2/TRX2 Antibody (7F674)
🥰Excellent
Catalog No. TMAY-02379
Anti-Thioredoxin 2/TRX2 Antibody (7F674) is a Rabbit antibody targeting Thioredoxin 2/TRX2. Anti-Thioredoxin 2/TRX2 Antibody (7F674) can be used in IHC-P.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Thioredoxin 2/TRX2 Antibody (7F674) is a Rabbit antibody targeting Thioredoxin 2/TRX2. Anti-Thioredoxin 2/TRX2 Antibody (7F674) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 7F674 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human TXN2 in human small intestine with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human TXN2 in human kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Thioredoxin-2 / TXN2 (rh Thioredoxin-2 / TXN2; TMPY-02084; Q99757; Thr60-Gly166). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Thioredoxin-2, also known as TXN2, MTRX and TRX2, is a member of the thioredoxin family. Tryparedoxins (TXN) are thioredoxin-related proteins which, as trypanothione:peroxiredoxin oxidoreductases, constitute the trypanothione-dependent antioxidant defense and may also serve as substrates for ribonucleotide reductase in trypanosomatids. Thioredoxin-2 / TXN2 contains one thioredoxin domain. It is widely expressed in adult (at protein level) and fetal tissues. Human Thioredoxin-2 / TXN2 is a small redox protein important in cellular antioxidant defenses, as well as in the regulation of apoptosis. Thioredoxin-2 / TXN2 has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Thioredoxin-2 / TXN2 could be involved in the resistance to anti-tumor agents. It possesses a dithiol-reducing activity. Thioredoxin-2 / TXN2 plays an important role in protecting the mitochondria against oxidative stress and in sensitizing the cells to ROS-induced apoptosis. Mammalian Thioredoxin-2 / TXN2 is a mitochondrial isoform of highly evolutionary conserved thioredoxins. Thioredoxins are small ubiquitous protein-disulfide oxidoreductases implicated in a large variety of biological functions. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human Thioredoxin-2 / TXN2 protein (TMPY-02084) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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