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Isoscopoletin

Name: Isoscopoletin
Brand: TargetMol
SKU: T3815
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3815Cas No. 776-86-3

Alias 7-Methoxyesculetin, 6-Hydroxy-7-methoxycoumarin

Isoscopoletin (7-Methoxyesculetin) is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of 6, 7-dimethoxy-2h-chromen-2-one.

Isoscopoletin

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Purity: 99.76%

Catalog No. T3815Alias 7-Methoxyesculetin, 6-Hydroxy-7-methoxycoumarinCas No. 776-86-3

Isoscopoletin (7-Methoxyesculetin) is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of 6, 7-dimethoxy-2h-chromen-2-one.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$31	In Stock	In Stock
10 mg	$56	In Stock	In Stock
25 mg	$92	In Stock	In Stock
50 mg	$133	-	In Stock
100 mg	$198	Backorder	Backorder
200 mg	$295	Backorder	Backorder
1 mL x 10 mM (in DMSO)	$35	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.76%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Isoscopoletin (7-Methoxyesculetin) is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of 6, 7-dimethoxy-2h-chromen-2-one.
Synonyms	7-Methoxyesculetin, 6-Hydroxy-7-methoxycoumarin

Chemical Properties

Molecular Weight	192.17
Formula	C₁₀H₈O₄
Cas No.	776-86-3
Smiles	COc1cc2oc(=O)ccc2cc1O
Relative Density.	1.37 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Chloroform, Dichloromethane, Ethyl Acetate, Acetone: Soluble

DMSO: 35 mg/mL (182.13 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (10.41 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.2037 mL	26.0186 mL	52.0373 mL	260.1863 mL
5 mM	1.0407 mL	5.2037 mL	10.4075 mL	52.0373 mL
10 mM	0.5204 mL	2.6019 mL	5.2037 mL	26.0186 mL
20 mM	0.2602 mL	1.3009 mL	2.6019 mL	13.0093 mL
50 mM	0.1041 mL	0.5204 mL	1.0407 mL	5.2037 mL
100 mM	0.0520 mL	0.2602 mL	0.5204 mL	2.6019 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc