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TargetMol | Compound Library

Anti-Neurodegenerative Disease Compound Library

Catalog No. L2620

Neurodegenerative disorders, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), spinal muscular atrophy (SMA), and amyotrophic lateral sclerosis (ALS), are incurable and debilitating conditions characterized by progressive degeneration of specific neurons within the brains of affected individuals. Neurodegenerative diseases have become an enormous economic burden that is projected to grow significantly over the next few decades in the absence of any new therapeutic interventions. Drugs for the central nervous system, including neurodegenerative diseases, that entered clinical development, have a considerably lower probability of reaching the marketplace (7%) than the industry average across other therapeutic areas (15%), and require a longer time for development and regulatory approval (average of 12.6 years) compared with most other diseases (e.g., 6.3 years for cardiovascular and 7.5 years for gastrointestinal indications). In this compound library, TargetMol collects 2154 compounds related to neurodegenerative diseases having therapeutic effect or acting on neurodegenerative disease-related targets.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2620

Anti-Neurodegenerative Disease Compound Library
sizeIn stock
  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 2154 compounds related to neurodegenerative diseases can be used for HTS or HCS;
  • Targets include AchE, NMDA, CGRP, β -secretase, γ -secretase, Dopamine receptor, Adenosine receptor, 5-HT receptor, etc.;
  • Some of them are FDA-approved;
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

5-HT Receptor
AChR
Dopamine Receptor
Adrenergic Receptor
GABA Receptor
Apoptosis
GluR
Autophagy
Opioid Receptor
AChE
Histamine Receptor
Endogenous Metabolite
NMDAR
PDE
iGluR
Beta Amyloid
COX
MAO
Gamma-secretase
Monoamine Oxidase
JNK
Serotonin Transporter
Antibacterial
Reactive Oxygen Species
NF-κB
PPAR
Norepinephrine
Adenosine Receptor
GSK-3
Potassium Channel
Caspase
Sodium Channel
Calcium Channel
P450
Parasite
Influenza Virus
HIV Protease
CaMK
Nrf2
TNF
LRRK2
BACE
Mitophagy
ERK
CDK
Ferroptosis
Antifungal
Mitochondrial Metabolism
Beta-Secretase
Dehydrogenase
TRP/TRPV Channel
IL Receptor
Cannabinoid Receptor
Antibiotic
Transferase
Bcr-Abl
Akt
Src
p38 MAPK
Phosphatase
P-gp
NO Synthase
Estrogen/progestogen Receptor
PI3K
Virus Protease
GlyT
ROS
MMP
DNA/RNA Synthesis
Phospholipase
Imidazoline Receptor
Antioxidant
PARP
BCL
OX Receptor
Interleukin
IκB/IKK
FLT
Sigma receptor
Microtubule Associated
Adenylyl cyclase
MRP
Wnt/beta-catenin
VEGFR
PKC
Drug Metabolite
MT Receptor
P2X Receptor
Aurora Kinase
Lipoxygenase
Sirtuin
HDAC
AMPK
MEK
c-Kit
Chloride channel
LPL Receptor
P2Y Receptor
Melatonin Receptor
PKA
AAK1 (AP2 associated kinase 1)
FAAH
EGFR
SARS-CoV
S1P Receptor
NOS
Carbonic Anhydrase
ROR
Histone Methyltransferase
RAAS
ABC
JAK
HSV
CCR
Epigenetic Reader Domain
IGF-1R
mTOR
Prostaglandin Receptor
Trk receptor
Retinoid Receptor
FGFR
Neurokinin receptor
Anti-infection
HMG-CoA Reductase
Tyrosinase
Amino Acids and Derivatives
NADPH
Histone Demethylase
Estrogen Receptor/ERR
Rho
Glucocorticoid Receptor
Glucosidase
Epoxide Hydrolase
TGF-beta/Smad
MAPK
Histone Acetyltransferase
Casein Kinase
c-Fms
NOD
S6 Kinase
HIF/HIF Prolyl-Hydroxylase
p53
HER
advanced glycation end products
Transaminase
Integrin
c-Met/HGFR
IFNAR
DYRK
Progesterone Receptor
HBV
Cysteine Protease
FXR
Aryl Hydrocarbon Receptor
CSF-1R
Immunology/Inflammation related
Topoisomerase
UGT
PAFR
Raf
BTK
Antifection
Monoamine Transporter
Guanylate cyclase
Stearoyl-CoA Desaturase (SCD)
PGE Synthase
Antiviral
STING
Free radical scavengers
transporter
Decarboxylase
RSV
ATM/ATR
Reverse Transcriptase
STAT
CRISPR/Cas9
GPR
CGRP Receptor
Gap Junction Protein
Ras
FAK
NOD-like Receptor (NLR)
Proteasome
ATPase
Monocarboxylate transporter
NPC1L1
HCV Protease
Arrestin
Na+/Ca2+ Exchanger
RAR/RXR 
Glutathione Peroxidase
GTPase
OCT
Hck
Serine/threonin kinase
Liver X Receptor
Nucleoside Antimetabolite/Analog
RANKL/RANK
ROCK
IAP
Annexin A
E1/E2/E3 Enzyme
Adiponectin receptor
LDL
GRK
Hexokinase
Neuropeptide Y Receptor
PAK
PDGFR
DNA Alkylation
Bombesin Receptor
Somatostatin
Chk
PAD
DUB
Androgen Receptor
Indoleamine 2,3-Dioxygenase (IDO)
Telomerase
SGLT
Acyltransferase
OAT
HSP
TLR
GluCls
PAI-1
ALK
Neprilysin
GST
Aromatase
PDK
Hydroxylase
HIF
Adenosine deaminase
SGK
NMU2R
Syk
DNA Methyltransferase
IRAK
Thrombin
MLK

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