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Anti-PNLIP Antibody (1E325) is a Rabbit antibody targeting PNLIP. Anti-PNLIP Antibody (1E325) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $268 | 7-10 days |
Description | Anti-PNLIP Antibody (1E325) is a Rabbit antibody targeting PNLIP. Anti-PNLIP Antibody (1E325) can be used in IHC-P. |
Alias | PTL, PNLIPD, PL, pancreatic lipase |
Ig Type | Monoclonal Rabbit IgG |
Clone | 1E325 |
Reactivity | Human |
Verified Activity | Immunochemical staining of human PNLIP in human pancreas with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
Application | IHC-P |
Recommended Dose | IHC-P: 1:1000-1:4000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human PNLIP (rh PNLIP; TMPY-03222; P16233; Met1-Cys465). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | PNLIP is an enzyme that belongs to the lipase family. Secreted from the pancreas, PNLIP is the primary lipase that hydrolyzes dietary fat molecules in the human digestive system, converting triglyceride substrates found in ingested oils to monoglycerides and free fatty acids. Bile salts secreted from the liver and stored in gallbladder are released into the duodenum where they coat and emulsify large fat droplets into smaller droplets, thus increasing the overall surface area of the fat, which allows the lipase to break apart the fat more effectively. The resulting monomers (2 free fatty acids and one 2-monoacylglycerol) are then moved by way of peristalsis along the small intestine to be absorbed into the lymphatic system by a specialized vessel called a lacteal. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human PNLIP Protein (TMPY-03222) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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