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Anti-FABP4 Antibody (3V644) is a Rabbit antibody targeting FABP4. Anti-FABP4 Antibody (3V644) can be used in IHC-P,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $94 | 7-10 days | |
100 μL | $269 | 7-10 days |
Description | Anti-FABP4 Antibody (3V644) is a Rabbit antibody targeting FABP4. Anti-FABP4 Antibody (3V644) can be used in IHC-P,FCM. |
Alias | HEL-S-104, fatty acid binding protein 4, adipocyte, aP2, ALBP, A-FABP, AFABP |
Ig Type | Monoclonal Rabbit IgG |
Clone | 3V644 |
Reactivity | Human |
Verified Activity | 1. Immunochemical staining of human FABP4 in human lung cancer with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human FABP4 in human appendix with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). 3. Flow cytometric analysis of Human FABP4 expression on Hela cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human FABP4, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
Application | IHC-P,FCM |
Recommended Dose | IHC-P: 1:1000-1:4000; FCM: 1:25-1:100 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human FABP4 / ALBP / A-FABP (rh FABP4 / ALBP / A-FABP; TMPY-02103; P15090; Cys2-Ala132,29Ala/Thr). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, and FABP4, is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. Patients in the highest quartile of FABP4 presented a six-fold increased odds ratio for MS and a three-fold increased odds for LD, adjusted by age, sex, body-mass index and the antiretroviral therapy. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human FABP4 / ALBP / A-FABP protein (TMPY-02103) |
Antigen Species | Human |
Biology Area | Early Mesodermal Lineage Markers |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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