INHBE Protein, Human, Recombinant (hFc)

Catalog No. TMPY-05029 Copy Product Info

INHBE (Inhibin Subunit Beta E) is a Protein Coding gene. This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate an inhibin beta subunit. INHBE was identified as a novel putative hepatokine with hepatic gene expression that positively correlated with insulin resistance and body mass index in humans. The quantitative real time-PCR analysis also showed an increase in INHBE gene expression in independent liver samples from insulin-resistant human subjects. INHBE functions as a possible hepatokine to alter the whole-body metabolic status under obese insulin-resistant conditions. Diseases associated with INHBE include Brachydactyly, Type A2, and Liver Benign Neoplasm.

INHBE Protein, Human, Recombinant (hFc)

Catalog No. TMPY-05029

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Pack Size	Price	USA Stock	Global Stock
5 μg	$63	7-10 days	7-10 days
10 μg	$98	7-10 days	7-10 days
20 μg	$163	7-10 days	7-10 days
50 μg	$323	7-10 days	7-10 days
100 μg	$625	7-10 days	7-10 days

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Biological Activity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	INHBE (Inhibin Subunit Beta E) is a Protein Coding gene. This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate an inhibin beta subunit. INHBE was identified as a novel putative hepatokine with hepatic gene expression that positively correlated with insulin resistance and body mass index in humans. The quantitative real time-PCR analysis also showed an increase in INHBE gene expression in independent liver samples from insulin-resistant human subjects. INHBE functions as a possible hepatokine to alter the whole-body metabolic status under obese insulin-resistant conditions. Diseases associated with INHBE include Brachydactyly, Type A2, and Liver Benign Neoplasm.
Species	Human
Expression System	HEK293 Cells
Tag	N-hFc
Accession Number	P58166
Synonyms	inhibin β E,inhibin beta E
Construction	A DNA sequence encoding the human INHBE (NP_113667.1) (Thr237-Ser350) was expressed with the Fc region of human IgG1 at the N-terminus. Predicted N terminal: Glu
Protein Purity	> 90 % as determined by SDS-PAGE.
Molecular Weight	40.9 kDa (predicted)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	INHBE (Inhibin Subunit Beta E) is a Protein Coding gene. This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate an inhibin beta subunit. INHBE was identified as a novel putative hepatokine with hepatic gene expression that positively correlated with insulin resistance and body mass index in humans. The quantitative real time-PCR analysis also showed an increase in INHBE gene expression in independent liver samples from insulin-resistant human subjects. INHBE functions as a possible hepatokine to alter the whole-body metabolic status under obese insulin-resistant conditions. Diseases associated with INHBE include Brachydactyly, Type A2, and Liver Benign Neoplasm.

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Keywords

inhibin b E