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Anti-Ficolin 1/FCN1 Antibody (5X101)
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Catalog No. TMAY-01344
Alias ficolin 1, FCNA, FCN1
Anti-Ficolin 1/FCN1 Antibody (5X101) is a Mouse antibody targeting Ficolin 1/FCN1. Anti-Ficolin 1/FCN1 Antibody (5X101) can be used in IHC-P.
Anti-Ficolin 1/FCN1 Antibody (5X101)
Anti-Ficolin 1/FCN1 Antibody (5X101)
😃Good
Catalog No. TMAY-01344Alias ficolin 1, FCNA, FCN1
Anti-Ficolin 1/FCN1 Antibody (5X101) is a Mouse antibody targeting Ficolin 1/FCN1. Anti-Ficolin 1/FCN1 Antibody (5X101) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-Ficolin 1/FCN1 Antibody (5X101) is a Mouse antibody targeting Ficolin 1/FCN1. Anti-Ficolin 1/FCN1 Antibody (5X101) can be used in IHC-P. |
| Alias | ficolin 1, FCNA, FCN1 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 5X101 |
| Reactivity | Human |
| Verified Activity | Immunochemical staining of human FCN1 in human spleen with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ficolin 1/FCN1/FCNA (rh ficolin 1/FCN1/FCNA; TMPY-01028; NP_001994.2; Met1-Ala326). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. The Ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. Three Ficolins have been identified in humans: L-Ficolin, H-Ficolin and M-Ficolin (also referred to as Ficolin-2, -3 and -1, respectively). They are soluble oligomeric defence proteins with lectin-like activity and they are structurally similar to the human collectins, mannan-binding lectin (MBL) and surfactant protein A and D. Dysfunction or abnormal expressions of Ficolins may involved in the pathogenesis of human diseases including infectious and inflammatory diseases, autoimmune disease and clinical syndrome of preeclampsia. They are soluble oligomeric defence proteins with lectin-like activity and they are structurally similar to the human collectins, mannan-binding lectin (MBL) and surfactant protein A and D. Upon recognition of the infectious agent, the Ficolins act through two distinct routes: initiate the lectin pathway of complement activation through attached serine proteases (MASPs), and a primitive opsonophagocytosis thus limiting the infection and concurrently orchestrating the subsequent adaptive clonal immune response. Ficolin-1 (FCN1) is predominantly expressed in the peripheral blood leukocytes. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human ficolin 1/FCN1/FCNA protein (TMPY-01028) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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