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Prednisolone disodium phosphate
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Catalog No. T0208Cas No. 125-02-0
Alias Prednisolone phosphate sodium, Prednisolone 21-phosphate disodium
Prednisolone disodium phosphate, a synthetic glucocorticoid, has immunomodulating and anti-inflammatory properties.
Prednisolone disodium phosphate
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Purity: 99.16%
Catalog No. T0208Alias Prednisolone phosphate sodium, Prednisolone 21-phosphate disodiumCas No. 125-02-0
Prednisolone disodium phosphate, a synthetic glucocorticoid, has immunomodulating and anti-inflammatory properties.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 mg | $35 | In Stock | In Stock | |
| 200 mg | $48 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.16%
Appearance:Solid
Color:White
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Product Introduction
Prednisolone disodium phosphate AI Summary
Prednisolone disodium phosphate has demonstrated antiviral activity against SARS-CoV-2, exhibiting variable efficacy across different experimental assays. It showed a 7.31% inhibition rate in preventing induced cytotoxicity in Caco-2 cells at a concentration of 10 µM after 48 hours. In another assay with HRCE cells infected with the SARS-CoV-2 (USA-WA1/2020 strain) at MOI 0.4 after 96 hours, the compound recorded a low hit score of 0.07703, indicating limited effectiveness. Additionally, Prednisolone disodium phosphate displayed inhibition of the SARS-CoV-2 3CL-Pro protease with a 7.126% inhibition rate at 20 µM, measured by FRET response. However, it also showed negligible inhibition (-0.03%) of SARS-CoV-2 induced cytotoxicity in VERO-6 cells at 10 µM after 48 hours. These results suggest that while Prednisolone disodium phosphate has some antiviral properties, its efficacy may be limited and variable depending on the assay conditions and cell lines used..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Prednisolone disodium phosphate, a synthetic glucocorticoid, has immunomodulating and anti-inflammatory properties. |
| Synonyms | Prednisolone phosphate sodium, Prednisolone 21-phosphate disodium |
| Molecular Weight | 484.39 |
| Formula | C21H27Na2O8P |
| Cas No. | 125-02-0 |
| Smiles | [Na+].[Na+].C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)COP([O-])([O-])=O |
| Relative Density. | no data available |
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 1 mg/mL (2.06 mM), Sonication is recommended.  H2O: 100 mg/mL (206.45 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
DMSO/H2O
H2O
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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