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TROP-2 Protein,Human,Recombinant (aa 88-274, hFc)
(Synonyms: Tumor-associated calcium signal transducer 2, TROP2, TACSTD2, Membrane component chromosome 1 surface marker 1, Cell surface glycoprotein Trop-2) Copy Product InfoSynonyms: Tumor-associated calcium signal transducer 2, TROP2, TACSTD2, Membrane component chromosome 1 surface marker 1, Cell surface glycoprotein Trop-2
Catalog No. TMPJ-00205 Copy Product Info
Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions. TROP-2 Protein,Human,Recombinant (aa 88-274, hFc） is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-80 KDa and the accession number is P09758.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $54 | 7-10 days | 7-10 days | |
| 10 µg | $85 | 7-10 days | 7-10 days | |
| 20 µg | $136 | 7-10 days | 7-10 days | |
| 50 µg | $259 | 7-10 days | 7-10 days | |
| 100 µg | $419 | 7-10 days | 7-10 days | |
| 200 µg | $678 | 7-10 days | 7-10 days | |
| 500 µg | $1,300 | 7-10 days | 7-10 days | |
| 1 mg | $1,550 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Human TROP-2-Fc at 2μg/ml (100 μl/well) can bind Anti-Human TROP-2 mAb* .*: Biotinylated by NHS-biotin prior to testing. The ED50 of Anti-Human TROP-2 mAb* is 5.16 ng/ml. (Regularly tested) |
| Description | Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions. TROP-2 Protein,Human,Recombinant (aa 88-274, hFc） is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-80 KDa and the accession number is P09758. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | P09758 |
| Amino Acid | Thr88-Thr274 |
| Construction | Thr88-Thr274 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | Tumor-associated calcium signal transducer 2, TROP2, TACSTD2, Membrane component chromosome 1 surface marker 1, Cell surface glycoprotein Trop-2 |
| Research Background | Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions. |
| Molecular Weight | 60-80 KDa (reducing condition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: TROP-2 Protein,Human,Recombinant (aa 88-274, hFc) chemical structure | TROP-2 Protein,Human,Recombinant (aa 88-274, hFc) molecular weight
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