TROP-2 Protein,Human,Recombinant (aa 88-274, hFc)

Catalog No. TMPJ-00205 Copy Product Info

Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions. TROP-2 Protein,Human,Recombinant (aa 88-274, hFc） is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-80 KDa and the accession number is P09758.

TROP-2 Protein,Human,Recombinant (aa 88-274, hFc)

Catalog No. TMPJ-00205

Copy Product Info

TROP-2 Protein,Human,Recombinant (aa 88-274, hFc)

Pack Size	Price	USA Stock	Global Stock
5 μg	$54	7-10 days	7-10 days
10 μg	$85	7-10 days	7-10 days
20 μg	$136	7-10 days	7-10 days
50 μg	$259	7-10 days	7-10 days
100 μg	$419	7-10 days	7-10 days
200 μg	$678	7-10 days	7-10 days
500 μg	$1,300	7-10 days	7-10 days
1 mg	$1,550	7-10 days	7-10 days

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Biological Activity	Immobilized Human TROP-2-Fc at 2μg/ml (100 μl/well) can bind Anti-Human TROP-2 mAb* .: Biotinylated by NHS-biotin prior to testing. The ED50 of Anti-Human TROP-2 mAb is 5.16 ng/ml. (Regularly tested)
Description	Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions. TROP-2 Protein,Human,Recombinant (aa 88-274, hFc） is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-80 KDa and the accession number is P09758.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	P09758
Synonyms	Tumor-associated calcium signal transducer 2,TROP2,TACSTD2,Membrane component chromosome 1 surface marker 1,Cell surface glycoprotein Trop-2
Amino Acid	Thr88-Thr274
Construction	Thr88-Thr274
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight	60-80 KDa (reducing condition)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.