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TROP-2 Protein,Human,Recombinant (aa 88-274, hFc)

Catalog No. TMPJ-00205
Synonyms: Tumor-associated calcium signal transducer 2, TROP2, Cell surface glycoprotein Trop-2, TACSTD2, Membrane component chromosome 1 surface marker 1

Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.

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TROP-2 Protein,Human,Recombinant (aa 88-274, hFc)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 85.00
50 μg 5 days $ 259.00
500 μg 5 days $ 1,300.00
1 mg 5 days $ 1,550.00
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Biological Description
Technical Params
Product Properties
Description Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
Species Human
Expression System Human Cells
Tag C-Fc
Accession Number P09758
Synonyms Tumor-associated calcium signal transducer 2, TROP2, Cell surface glycoprotein Trop-2, TACSTD2, Membrane component chromosome 1 surface marker 1
Amino Acid Thr88-Thr274
Construction Recombinant Human Tumor-associated Calcium Signal Transducer 2 is produced by our Mammalian expression system and the target gene encoding Thr88-Thr274 is expressed with a human IgG1 Fc tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 60-80 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Research Background Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.

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Keywords

TROP-2 Protein,Human,Recombinant (aa 88-274, hFc) Tumor-associated calcium signal transducer 2 TROP-2 TROP2 TACSTD-2 Cell surface glycoprotein Trop-2 TACSTD2 TROP 2 Membrane component chromosome 1 surface marker 1 TACSTD 2 recombinant recombinant-proteins proteins protein

 

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