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Anti-CST6 Antibody (1U151)
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Catalog No. TMAY-00830
Alias N28197, ichq, cystatin E/M, 1110017E11Rik
Anti-CST6 Antibody (1U151) is a Mouse antibody targeting CST6. Anti-CST6 Antibody (1U151) can be used in IHC-P.
Anti-CST6 Antibody (1U151)
Anti-CST6 Antibody (1U151)
😃Good
Catalog No. TMAY-00830Alias N28197, ichq, cystatin E/M, 1110017E11Rik
Anti-CST6 Antibody (1U151) is a Mouse antibody targeting CST6. Anti-CST6 Antibody (1U151) can be used in IHC-P.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CST6 Antibody (1U151) is a Mouse antibody targeting CST6. Anti-CST6 Antibody (1U151) can be used in IHC-P. |
| Synonyms | N28197, ichq, cystatin E/M, 1110017E11Rik |
| Ig Type | Mouse IgG1 |
| Clone | 1U151 |
| Reactivity | Human |
| Specificity | Human CST6 |
| Verified Activity | Immunochemical staining of human CST6 in human skin with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
| Application | |
| Recommended Dose | IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Cystatin E / CST6 (rh Cystatin E / CST6; TMPY-00768; NP_001314.1; Met1-Met149). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Cystatin E/M, also referred to as CST6, is a member of type 2 cysteine proteinase inhibitors of the cystatin superfamily, and inhibits papain and cathepsin B. Cystatin E is a low molecular mass secreted protein existing in both a glycosylated (17 kDa) and an unglycosylated (14 kDa) form, with two characteristic intrachain disulfide bridges. Expression of cystatin M/E is found to be restricted to the epidermis, more specifically in the stratum granulosum, sweat glands, sebaceous glands, and the hair follicles. In addition to its function as a cysteine protease inhibitor, cystatin M/E also serves as a target for cross-linking by transglutaminases. Accordingly, cystatin M/E was suggested to be involved in barrier formation and maintenance. Furthermore, studies have revealed that cystatin M/E is frequently epigenetically inactivated during breast carcinogenesis, and thus be regarded as a candidate of tumour suppressor gene. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Cystatin E / CST6 protein (TMPY-00768) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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