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Anti-CD155/PVR Antibody (7L676) is a Mouse antibody targeting CD155/PVR. Anti-CD155/PVR Antibody (7L676) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $93 | 7-10 days | |
100 μL | $294 | 7-10 days |
Description | Anti-CD155/PVR Antibody (7L676) is a Mouse antibody targeting CD155/PVR. Anti-CD155/PVR Antibody (7L676) can be used in ELISA. |
Alias | TAGE4, PVS, poliovirus receptor, Necl-5, NECL5, HVED, CD155 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 7L676 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD155 extracellular domain (rh CD155; TMPY-01386; Met 1-Asn 343; P15151-1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS with 0.02% Tween 80, pH 7.0 |
Research Background | CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhesion, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
Conjucates | Unconjugated |
Immunogen | Recombinant Human CD155 protein (TMPY-01386) |
Antigen Species | Human |
Biology Area | Cancer Drug Targets |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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