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Acetyl-cyclosporin A aldehyde

Name: Acetyl-cyclosporin A aldehyde
Brand: TargetMol
SKU: T85549
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T85549Cas No. 121584-52-9

Acetyl-cyclosporin A aldehyde is a cyclosporin A derivative, a neurocalmodulin inhibitor and cyclophilin binder with potential anti-inflammatory, antitumor, and antiviral activity. It is used in studies of organ transplantation and autoimmune diseases.

Acetyl-cyclosporin A aldehyde

🥰Excellent

Purity: 99.76%

Catalog No. T85549Cas No. 121584-52-9

Pack Size	Price	Availability	Quantity
100 mg	$30	In Stock
200 mg	$44	In Stock

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Purity:99.76%

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COA HPLC MS

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	1232.59
Formula	C₆₂H₁₀₉N₁₁O₁₄
Cas No.	121584-52-9
Smiles	[C@H]([C@@H](CC=O)C)(OC(C)=O)[C@@]1(N(C)C(=O)[C@H]([C@@H](C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H]([C@H](C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@H](CC)NC1=O)[H]
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (40.56 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.8113 mL	4.0565 mL	8.1130 mL	40.5650 mL
5 mM	0.1623 mL	0.8113 mL	1.6226 mL	8.1130 mL
10 mM	0.0811 mL	0.4056 mL	0.8113 mL	4.0565 mL
20 mM	0.0406 mL	0.2028 mL	0.4056 mL	2.0282 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc