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Mn(Ⅲ) Protoporphyrin IX Chloride

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Catalog No. T83663Cas No. 120389-54-0
Alias Manganese(Ⅲ) Protoporphyrin IX Chloride

Mn(Ⅲ) Protoporphyrin IX Chloride (Manganese(Ⅲ) Protoporphyrin IX Chloride) is a metallated derivative of protoporphyrin IX, an experimental MRI relaxation enhancer.

Mn(Ⅲ) Protoporphyrin IX Chloride

Mn(Ⅲ) Protoporphyrin IX Chloride

😃Good
Purity: 97.62%
Catalog No. T83663Alias Manganese(Ⅲ) Protoporphyrin IX ChlorideCas No. 120389-54-0
Mn(Ⅲ) Protoporphyrin IX Chloride (Manganese(Ⅲ) Protoporphyrin IX Chloride) is a metallated derivative of protoporphyrin IX, an experimental MRI relaxation enhancer.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$49-In Stock
10 mgPreferential-In Stock
25 mgPreferential-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:97.62%
Appearance:Solid
Color:Brown
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Product Introduction

Bioactivity
Description
Mn(Ⅲ) Protoporphyrin IX Chloride (Manganese(Ⅲ) Protoporphyrin IX Chloride) is a metallated derivative of protoporphyrin IX, an experimental MRI relaxation enhancer.
In vitro
Mn(Ⅲ) Protoporphyrin IX Chloride is a metalloporphyrin. At a concentration of 10 μM, it up-regulates the mRNA expression of the genes encoding δ-aminolevulinic acid synthase and heme oxygenase (HO), which are responsible for catalyzing the rate-limiting steps of heme biosynthesis and degradation, respectively, in chicken embryo hepatocytes. [1]
SynonymsManganese(Ⅲ) Protoporphyrin IX Chloride
Chemical Properties
Molecular Weight651.03
FormulaC34H32ClMnN4O4
Cas No.120389-54-0
SmilesO=C(CCC1=C(C)C2=[N]3C1=CC4=C(CCC([O-])=O)C(C)=C5C=C6C(C=C)=C(C)C(C=C7C(C=C)=C(C)C8=C2)=[N]6[Mn+3]3([N-]78)([N-]54)[Cl-])[O-].[H+].[H+]
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
2 M NaOH: 8 mg/mL (12.29 mM), Sonication is recommended.
0.1 M Na2CO3: 4 mg/mL (6.14 mM), Sonication is recommended.
Solution Preparation Table
0.1 M Na2CO3/2 M NaOH
1mg5mg10mg50mg
1 mM1.5360 mL7.6801 mL15.3603 mL76.8014 mL
5 mM0.3072 mL1.5360 mL3.0721 mL15.3603 mL
2 M NaOH
1mg5mg10mg50mg
10 mM0.1536 mL0.7680 mL1.5360 mL7.6801 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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