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Anti-Phospho-PTEN (S380) Antibody (6S492)

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Catalog No. TMAC-03255
Alias TEP1, PTEN1, PTEN (p-Ser380), PTEN (p-S380), p-PTEN (Ser380), p-PTEN (S380), Phospho-PTEN (S380), Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Phosphatase and tensin like protein, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, MMAC1, MHAM, MGC11227, GLM2, DEC, BZS, 10q23del

Anti-Phospho-PTEN (S380) Antibody (6S492) is a Rabbit antibody targeting Phospho-PTEN (S380). Anti-Phospho-PTEN (S380) Antibody (6S492) can be used in WB,ICC.

Anti-Phospho-PTEN (S380) Antibody (6S492)

Anti-Phospho-PTEN (S380) Antibody (6S492)

😃Good
Catalog No. TMAC-03255Alias TEP1, PTEN1, PTEN (p-Ser380), PTEN (p-S380), p-PTEN (Ser380), p-PTEN (S380), Phospho-PTEN (S380), Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Phosphatase and tensin like protein, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, MMAC1, MHAM, MGC11227, GLM2, DEC, BZS, 10q23del
Anti-Phospho-PTEN (S380) Antibody (6S492) is a Rabbit antibody targeting Phospho-PTEN (S380). Anti-Phospho-PTEN (S380) Antibody (6S492) can be used in WB,ICC.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-PTEN (S380) Antibody (6S492) is a Rabbit antibody targeting Phospho-PTEN (S380). Anti-Phospho-PTEN (S380) Antibody (6S492) can be used in WB,ICC.
AliasTEP1, PTEN1, PTEN (p-Ser380), PTEN (p-S380), p-PTEN (Ser380), p-PTEN (S380), Phospho-PTEN (S380), Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Phosphatase and tensin like protein, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, MMAC1, MHAM, MGC11227, GLM2, DEC, BZS, 10q23del
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-2000; ICC: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundAs human tumors progress to advanced stages, one genetic alteration that occurs at high frequency is a loss of heterozygosity (LOH) at chromosome 10q23. Mapping of homozygous deletions on this chromosome led to the isolation of the PTEN gene, also designated MMAC1 (for mutated in multiple advanced cancers) and TEP1. This candidate tumor suppressor gene exhibits a high frequency of mutations in human glioblastomas and is also mutated in other cancers, including sporadic brain, breast, kidney and prostate cancers. PTEN has been associated with Cowden disease, an autosomal dominant cancer predisposition syndrome. The PTEN gene product is a putative protein tyrosine phosphatase that is localized to the cytoplasm and shares extensive homology with the cytoskeletal proteins tensin and auxilin. Gene transfer studies have indicated that the phosphatase domain of PTEN is essential for growth suppression of glioma cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human PTEN around the phosphorylation site of Ser380
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 55 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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