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Adiphenine hydrochloride

Name: Adiphenine hydrochloride
Brand: TargetMol
SKU: T0072
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T0072Cas No. 50-42-0

Alias Spasnil, Sentiv, Patrovina, Adiphenine HCl

Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.

Adiphenine hydrochloride

🥰Excellent

Purity: 99.53%

Catalog No. T0072Alias Spasnil, Sentiv, Patrovina, Adiphenine HClCas No. 50-42-0

Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.

Pack Size	Price	USA Warehouse	Global Warehouse
200 mg	$30	In Stock	In Stock
500 mg	$60	In Stock	In Stock
1 g	$87	-	In Stock
5 g	$213	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.53%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.
Targets&IC50	α3β4 nAChR:1.8 µM (IC50), α1 nAChR:1.9 µM (IC50), α4β2 nAChR:3.7 µM (IC50), α4β4 nAChR:6.3 µM (IC50)
Synonyms	Spasnil, Sentiv, Patrovina, Adiphenine HCl

Chemical Properties

Molecular Weight	347.88
Formula	C₂₀H₂₅NO₂·HCl
Cas No.	50-42-0
Smiles	O=C(OCCN(CC)CC)C(C1=CC=CC=C1)C2=CC=CC=C2.[H]Cl
Relative Density.	1.0555 g/cm3 (Estimated)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (143.73 mM), Sonication is recommended.

H2O: 64 mg/mL (183.97 mM), Sonication is recommended.

Ethanol: 15 mg/mL (43.12 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2.5 mg/mL (7.19 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	2.8746 mL	14.3728 mL	28.7455 mL	143.7277 mL
5 mM	0.5749 mL	2.8746 mL	5.7491 mL	28.7455 mL
10 mM	0.2875 mL	1.4373 mL	2.8746 mL	14.3728 mL
20 mM	0.1437 mL	0.7186 mL	1.4373 mL	7.1864 mL

DMSO/H2O

	1mg	5mg	10mg	50mg
50 mM	0.0575 mL	0.2875 mL	0.5749 mL	2.8746 mL
100 mM	0.0287 mL	0.1437 mL	0.2875 mL	1.4373 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc