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Anti-TCPTP Antibody (6E858)
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Catalog No. TMAY-03465
Alias TC-PTP, TCPTP, TCELLPTP, PTPT, PTN2, protein tyrosine phosphatase, non-receptor type 2
Anti-TCPTP Antibody (6E858) is a Rabbit antibody targeting TCPTP. Anti-TCPTP Antibody (6E858) can be used in ELISA.
Anti-TCPTP Antibody (6E858)
Anti-TCPTP Antibody (6E858)
😃Good
Catalog No. TMAY-03465Alias TC-PTP, TCPTP, TCELLPTP, PTPT, PTN2, protein tyrosine phosphatase, non-receptor type 2
Anti-TCPTP Antibody (6E858) is a Rabbit antibody targeting TCPTP. Anti-TCPTP Antibody (6E858) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-TCPTP Antibody (6E858) is a Rabbit antibody targeting TCPTP. Anti-TCPTP Antibody (6E858) can be used in ELISA. |
| Alias | TC-PTP, TCPTP, TCELLPTP, PTPT, PTN2, protein tyrosine phosphatase, non-receptor type 2 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 6E858 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse PTPN2 / TC-PTP (rM PTPN2 / TC-PTP; TMPY-02369; Q06180-1; Ser2-Asn314). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Tyrosine-protein phosphatase non-receptor type 2, also known as T-cell protein-tyrosine phosphatase, PTPN2 and PTPT, is a cytoplasm protein that belongs to the protein-tyrosine phosphatase family and Non-receptor class 1 subfamily. Members of the protein tyrosine phosphatase ( PTP ) family share a highly conserved catalytic motif, which is essential for the catalytic activity. TC-PTP / PTPN2 is a cytosolic tyrosine phosphatase that functions as a negative regulator of a variety of tyrosine kinases and other signaling proteins. The expression of TC-PTP / PTPN2 plays a role of tumor suppressor and may modulate response to treatment. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. TC-PTP / PTPN2 is an enzyme that is essential for the proper functioning of the immune system and that participates in the control of cell proliferation, and inflammation. TC-PTP / PTPN2 was identified as a negative regulator of NUP214-ABL1 kinase activity. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse PTPN2 / TC-PTP Protein (TMPY-02369) |
| Antigen Species | Mouse |
| Biology Area | Phosphatases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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