Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CYP1B1-IN-4, a 2,4-diarylthiazole compound, exhibits selective inhibition of CYP1B1 (IC50=0.2 nM), demonstrating minimal cytotoxicity and high stability in human and rat liver microsomes [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 55.00 | |
10 mg | In stock | $ 89.00 | |
25 mg | In stock | $ 178.00 | |
50 mg | In stock | $ 289.00 | |
100 mg | In stock | $ 428.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 75.00 |
Description | CYP1B1-IN-4, a 2,4-diarylthiazole compound, exhibits selective inhibition of CYP1B1 (IC50=0.2 nM), demonstrating minimal cytotoxicity and high stability in human and rat liver microsomes [1]. |
Targets&IC50 | CYP1B1:0.2 nM, CYP1A1:3.98 μM |
In vitro |
CYP1B1-IN-4 (Compound 15) (1 nM-10 μM) inhibits CYP1A1 with an IC50 of 3.82 μM.[1] Cyp1b1-IN-4 (100 μM; 72 h) is non-cytotoxic to HEK293 cells.[1] |
Molecular Weight | 322.38 |
Formula | C18H14N2O2S |
CAS No. | 2685779-55-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 32.24 mg/mL (100 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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CYP1B1-IN-4 2685779-55-7 Metabolism P450 inhibitor inhibit