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AFP Protein, Canine, Recombinant (His)

(Synonyms: α-fetoprotein, α-feto, α-1-fetoprotein, HPAFP, FETA, Alpha-fetoprotein, Alpha-feto, Alpha-1-fetoprotein, AFPD, AFP) Copy Product Info

Synonyms: α-fetoprotein, α-feto, α-1-fetoprotein, HPAFP, FETA, Alpha-fetoprotein, Alpha-feto, Alpha-1-fetoprotein, AFPD, AFP

Catalog No. TMPK-01097 Copy Product Info
Alpha-fetoprotein is a shuttle protein that delivers nutrients through receptor-mediated endocytosis to embryotic cells. In adults, alpha-fetoprotein can shuttle drugs into alpha-fetoprotein receptor-positive myeloid-derived suppressor, regenerating and also cancer cells. Drugs with high-binding affinity to alpha-fetoprotein can activate or deplete targeted cells. Myeloid-derived suppressor cells activation leads to immune suppression that can be used for treating autoimmune diseases. AFP Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 67.71 kDa and the accession number is Q8MJU5.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$567-10 days7-10 days
10 μg$887-10 days7-10 days
20 μg$1437-10 days7-10 days
50 μg$2787-10 days7-10 days
100 μg$4657-10 days7-10 days
200 μg$8397-10 days7-10 days
500 μg$1,8507-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Alpha-fetoprotein is a shuttle protein that delivers nutrients through receptor-mediated endocytosis to embryotic cells. In adults, alpha-fetoprotein can shuttle drugs into alpha-fetoprotein receptor-positive myeloid-derived suppressor, regenerating and also cancer cells. Drugs with high-binding affinity to alpha-fetoprotein can activate or deplete targeted cells. Myeloid-derived suppressor cells activation leads to immune suppression that can be used for treating autoimmune diseases. AFP Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 67.71 kDa and the accession number is Q8MJU5.
Species
Canine
Expression System
HEK293 Cells
TagC-His
Accession NumberQ8MJU5
ConstructionArg19-Val609
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Synonymsα-fetoprotein, α-feto, α-1-fetoprotein, HPAFP, FETA, Alpha-fetoprotein, Alpha-feto, Alpha-1-fetoprotein, AFPD, AFP
Research Background
Chemical Properties
Molecular Weight67.71 kDa (predicted). Due to glycosylation, the protein migrates to 68-70 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: AFP Protein, Canine, Recombinant (His) chemical structure | AFP Protein, Canine, Recombinant (His) molecular weight