TWEAK/TNFSF12 Protein, Human, Recombinant

Name: TWEAK/TNFSF12 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPS-00141
Price: 71 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: TNFSF12, TNF-related weak inducer of apoptosis, DR3LG, Apo3-Ligand) Copy Product Info

Synonyms: TNFSF12, TNF-related weak inducer of apoptosis, DR3LG, Apo3-Ligand

Catalog No. TMPS-00141 Copy Product Info

TWEAK/TNFSF12 Protein, Human, Recombinant is expressed in CHO Cells. The accession number is Q4ACW9.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$71	-	In Stock
10 µg	$113	-	In Stock
20 µg	$178	7-10 days	7-10 days
50 µg	$339	7-10 days	7-10 days
100 µg	$535	7-10 days	7-10 days
200 µg	$846	7-10 days	7-10 days
500 µg	$1,550	7-10 days	7-10 days
1 mg	$2,480	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as analyzed by SDS-PAGE > 95% as analyzed by HPLC

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 1.0 ng/ml, measured in a cell cytotoxicity assay using HTB-38 (HT-29) cells.
Description	TWEAK/TNFSF12 Protein, Human, Recombinant is expressed in CHO Cells. The accession number is Q4ACW9.
Species	Human
Expression System	CHO Cells
Tag	Tag Free
Accession Number	Q4ACW9
Construction	Arg99-His249
Protein Purity	> 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	TNFSF12, TNF-related weak inducer of apoptosis, DR3LG, Apo3-Ligand
Research Background	TWEAK, short for TNF-related weak inducer of apoptosis, is also known as TNFSF12 and DR3LG. It is a type II transmembrane protein belonging to the TNF superfamily. It is expressed widely in many tissues, such as the heart, skeletal muscle, spleen and peripheral blood. Binding of TWEAK to its receptor TWEAKR induces NF-κB activation, chemokine secretion and apoptosis in certain cell types. TWEAK has also been reported to promote endothelial cell proliferation and migration, thus serving as a regulator of angiogenesis.

Chemical Properties

Molecular Weight

20-22 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.