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Anti-CENPC Antibody (3X906)
😃Good
Catalog No. TMAC-00815
Alias MIF2, Interphase centromere complex protein 7, ICEN7, hcp-4, Centromere protein C 1, Centromere protein C, Centromere autoantigen C1, Centromere autoantigen C, CENPC1, CENPC_HUMAN, CENP-C 1, CENP-C
Anti-CENPC Antibody (3X906) is a Rabbit antibody targeting CENPC. Anti-CENPC Antibody (3X906) can be used in FCM,ICC,IF,IHC,IP,WB.
Anti-CENPC Antibody (3X906)
Anti-CENPC Antibody (3X906)
😃Good
Catalog No. TMAC-00815Alias MIF2, Interphase centromere complex protein 7, ICEN7, hcp-4, Centromere protein C 1, Centromere protein C, Centromere autoantigen C1, Centromere autoantigen C, CENPC1, CENPC_HUMAN, CENP-C 1, CENP-C
Anti-CENPC Antibody (3X906) is a Rabbit antibody targeting CENPC. Anti-CENPC Antibody (3X906) can be used in FCM,ICC,IF,IHC,IP,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-CENPC Antibody (3X906) is a Rabbit antibody targeting CENPC. Anti-CENPC Antibody (3X906) can be used in FCM,ICC,IF,IHC,IP,WB. |
| Synonyms | MIF2, Interphase centromere complex protein 7, ICEN7, hcp-4, Centromere protein C 1, Centromere protein C, Centromere autoantigen C1, Centromere autoantigen C, CENPC1, CENPC_HUMAN, CENP-C 1, CENP-C |
| Ig Type | IgG |
| Clone | 3X906 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of CENPC on K562 cell lysate using anti-CENPC antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-CENPC antibody. Counter stained with hematoxylin. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6) for 20 mins. 3. Immunohistochemical analysis of paraffin-embedded rat heart tissue using anti-CENPC antibody. Counter stained with hematoxylin. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6) for 20 mins. 4. ICC staining CENPC in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. Flow cytometric analysis of K562 cells with CENPC antibody at 1/100 dilution (yellow) compared with an unlabelled control (cells without incubation with primary antibody; purple). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.      |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; IP: 1:10-50; FCM: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | A replicated chromosome includes two kinetochores that control chromosome segregation during mitosis. The evolutionarily conserved Centromere Protein-C, CENP-C, is a kinetochore assembly protein. CENP-C is located on the fibers of the kinetochore and constitutes a kinetochore organizing center that tightly associates with DNA. CENP-C is necessary for the formation of a functional centromere, which indicates that CENP-C is important for mitotic progression. In addition, CENP-C is lost from centromeres during herpes simplex virus 1 infection, causing substantial structural changes in the kinetochore, which suggests that the structure of CENP-C is regulated during the cell cycle. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: human CENPC aa 400-600 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 107 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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