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PROTAC BET-binding moiety 2

Name: PROTAC BET-binding moiety 2
Brand: TargetMol
SKU: T12558
Rating: 4.5 (1 reviews)

🥰Excellent

Catalog No. T12558Cas No. 916493-82-8

PROTAC BET-binding moiety 2 is an inhibitor of the BET bromodomain.

PROTAC BET-binding moiety 2

🥰Excellent

Catalog No. T12558Cas No. 916493-82-8

PROTAC BET-binding moiety 2 is an inhibitor of the BET bromodomain.

Product information is being updated, if you want to purchase, please click the bulk custom button.

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Product Introduction

Bioactivity

Description

PROTAC BET-binding moiety 2 is an inhibitor of the BET bromodomain.

Chemical Properties

Molecular Weight	444.89
Formula	C₂₀H₁₇ClN₄O₄S
Cas No.	916493-82-8
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 42.86 mg/mL (96.34 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2477 mL	11.2387 mL	22.4775 mL	112.3873 mL
5 mM	0.4495 mL	2.2477 mL	4.4955 mL	22.4775 mL
10 mM	0.2248 mL	1.1239 mL	2.2477 mL	11.2387 mL
20 mM	0.1124 mL	0.5619 mL	1.1239 mL	5.6194 mL
50 mM	0.0450 mL	0.2248 mL	0.4495 mL	2.2477 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc