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Fallypride
Catalog No. T70302 Copy Product Info
Purity: 99.86%
🥰Excellent
Fallypride is a potent and selective dopamine D2/D3 receptor antagonist.
Fallypride
Copy Product Info🥰Excellent
Catalog No. T70302
Fallypride is a potent and selective dopamine D2/D3 receptor antagonist.
Cas No. 166173-78-0
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $378 | - | In Stock | |
| 5 mg | $886 | - | In Stock | |
| 10 mg | $1,090 | - | In Stock | |
| 25 mg | $1,750 | - | In Stock | |
| 50 mg | $2,180 | - | In Stock | |
| 100 mg | $2,800 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $712 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
Batch Information
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Purity:99.86%
ee:100%
Appearance:Liquid
Color:Transparent
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Product Introduction
Fallypride AI Summary
Fallypride exhibits bioactivity as a dopamine receptor modulator and shows high affinity for dopamine D2short (Ki = 2.1 nM), dopamine D2long (Ki = 2.2 nM), and dopamine D3 (Ki = 1.6 nM) receptors. It functions as an antagonist at the dopamine D2 receptor with an IC50 value of 5.0 nM and has been reported to have a Ki value of 0.097 nM for the human D2 receptor transfected in HEK cells. Additionally, Fallypride shows moderate affinity for serotonin 5-HT1A (Ki = 1100.0 nM) and 5-HT2 (Ki = 3700.0 nM) receptors, as well as for adrenergic-alpha-1 receptors (Ki = 970.0 nM). The compound also possesses moderate lipophilicity with a log D value of 2.66 at pH 7.4. Furthermore, Fallypride displays antiviral activity against SARS-CoV-2, inhibiting SARS-CoV-2 induced cytotoxicity in VERO-6 cells with IC50 values greater than 20000.0 nM and 19952.62 nM in two separate assays, highlighting its potential as an antiviral agent..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Fallypride is a potent and selective dopamine D2/D3 receptor antagonist. |
| Molecular Weight | 364.45 |
| Formula | C20H29FN2O3 |
| Cas No. | 166173-78-0 |
| Smiles | C(NC[C@H]1N(CC=C)CCC1)(=O)C2=C(OC)C(OC)=CC(CCCF)=C2 |
| Storage | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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