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CCP peptide acetate

Name: CCP peptide acetate
Brand: TargetMol
SKU: TP1409L
Rating: 4.5 (1 reviews)

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Catalog No. TP1409L

Alias CCP peptide acetate(277748-59-1 Free base)

CCP peptide acetate is a synthetic cyclic citrullinated peptide (CCP). CCP peptide acetate can be used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide acetate functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA).

CCP peptide acetate

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Catalog No. TP1409LAlias CCP peptide acetate(277748-59-1 Free base)

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$197	4-6 weeks	4-6 weeks
5 mg	$464	4-6 weeks	4-6 weeks
10 mg	$785	4-6 weeks	4-6 weeks
25 mg	$1,241	4-6 weeks	4-6 weeks
50 mg	$1,859	4-6 weeks	4-6 weeks
100 mg	$2,789	4-6 weeks	4-6 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	CCP peptide acetate is a synthetic cyclic citrullinated peptide (CCP). CCP peptide acetate can be used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide acetate functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA).
In vitro	Instructions 1. Material preparation: 1) CCP peptide acetate: Prepare the solution according to the experimental requirements, the concentration is usually 1-10 μg/mL. 2) Serum sample: serum collected from patients. 3) Determined enzyme-labeled substrate system for detecting antibody reactions. 2. Experimental steps: 1) Add CCP peptide acetate solution to the pretreated 96-well plate. 2) Add patient serum sample, usually diluted 1:100 or adjusted according to experimental conditions. 3) Incubate the reaction plate for 1-2 hours. 4) Use appropriate secondary antibody (such as anti-human IgG conjugated to enzyme) for reaction. 5) Add enzyme-labeled substrate, observe color change, and measure absorbance at the corresponding wavelength using a microplate reader. The above information is based on published literature. Experimental procedures should be appropriately modified to meet specific research demands.
Synonyms	CCP peptide acetate(277748-59-1 Free base)

Chemical Properties

Molecular Weight	2401.52
Formula	C₈₉H₁₄₉N₄₁O₃₄S₂
Smiles	O=C([C@H](CSSC[C@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@](NC([C@@H](NC([C@@H](NC([C@@H](NC1=O)CCC(N)=O)=O)CCC(O)=O)=O)CO)=O)([H])[C@H](O)C)=O)CCCNC(N)=O)=O)=O)CCCNC(N)=N)=O)CO)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(NCC(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)NC([C@H](CCC(N)=O)NC([C@@H](N)CC2=CN=CN2)=O)=O)N[C@H]1CC3=CN=CN3.CC(O)=O
Relative Density.	no data available
Sequence	His-Gln-Cys-His-Gln-Glu-Ser-Thr-{Cit}-Gly-Arg-Ser-Arg-Gly-Arg-Cys-Gly-Arg-Ser-Gly-Ser (Disulfide bridge: Cys3-Cys16)
Sequence Short	HQCHQEST-{Cit}-GRSRGRCGRSGS (Disulfide bridge: Cys3-Cys16)

Storage & Solubility Information

Storage

keep away from moisture,store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

CCP peptide Acetate