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CCP peptide acetate

Catalog No. TP1409L   CAS TP1409L
Synonyms: CCP peptide acetate(277748-59-1 Free base)

CCP peptide acetate is a synthetic cyclic citrullinated peptide (CCP). CCP peptide acetate can be used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide acetate functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA).

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CCP peptide acetate Chemical Structure
CCP peptide acetate, CAS TP1409L
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Biological Description
Chemical Properties
Storage & Solubility Information
Description CCP peptide acetate is a synthetic cyclic citrullinated peptide (CCP). CCP peptide acetate can be used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide acetate functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA).
In vitro CCP peptide acetate is used as a new antigenic substrate in anti-CCP ELISA to detect anti-citrullinated protein antibodies (ACPAs). The anti-CCP ELISA is extremely specific (98%), with a reasonable sensitivity (68%). The anti-CCP ELISA is very useful for diagnostic and therapeutic strategies in rheumatoid arthritis (RA)[3].
Synonyms CCP peptide acetate(277748-59-1 Free base)
Molecular Weight 2401.52
Formula C89H149N41O34S2
CAS No. TP1409L

Storage

keep away from moisture,store at low temperature,keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Puszczewicz M, et al. Role of anti-citrullinated protein antibodies in diagnosis and prognosis of rheumatoid arthritis. Arch Med Sci. 2011 Apr;7(2):189-94. 2. Söderlin MK, et al. Antibodies against cyclic citrullinated peptide (CCP) and levels of cartilage oligomeric matrix protein (COMP) in very early arthritis: relation to diagnosis and disease activity. Scand J Rheumatol. 2004;33(3):185-8. 3. Schellekens GA, et al. The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide. Arthritis Rheum. 2000 Jan;43(1):155-63.

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Keywords

CCP peptide acetate TP1409L Others CCP peptide acetate(277748-59-1 Free base) CCP peptide Acetate inhibitor inhibit

 

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