Shopping Cart
Remove All
Your shopping cart is currently empty
Opucolimab represents a highly specialized humanized monoclonal antibody specifically engineered to target the human Claudin 18.2 protein with exceptional binding affinity and selectivity, effectively facilitating the measurable detection and neutralization of target-positive malignant cells across various preclinical experimental models to evaluate the efficacy of antibody-drug conjugates during strictly monitored laboratory observation periods and molecular investigations to ensure experimental accuracy.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | Inquiry | Inquiry | Inquiry |
| Description | Opucolimab represents a highly specialized humanized monoclonal antibody specifically engineered to target the human Claudin 18.2 protein with exceptional binding affinity and selectivity, effectively facilitating the measurable detection and neutralization of target-positive malignant cells across various preclinical experimental models to evaluate the efficacy of antibody-drug conjugates during strictly monitored laboratory observation periods and molecular investigations to ensure experimental accuracy. |
| In vitro | In functional assays using CLDN18.2-expressing gastric cancer cell lines, Opucolimab (as an ADC) induced rapid endocytosis and demonstrated cytotoxic activity with IC50 values of 0.01-0.5 nM [1]. |
| In vivo | In human gastric cancer CDX and PDX mouse models, systemic administration of Opucolimab significantly suppressed tumor growth and induced tumor regression at low doses [1]. |
| Synonyms | HLX43 antibody, HLX20 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | PD-L1 |
| Cas No. | 2251771-79-4 |
| Isotype | IgG1 |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
| Size | Quantity | Unit Price | Amount | Operation |
|---|

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.