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Anti-Phospho-RPA2 (T21) Antibody (1G657)

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Catalog No. TMAC-03627

Anti-Phospho-RPA2 (T21) Antibody (1G657) is a Rabbit antibody targeting Phospho-RPA2 (T21). Anti-Phospho-RPA2 (T21) Antibody (1G657) can be used in WB,IP.

Anti-Phospho-RPA2 (T21) Antibody (1G657)

Anti-Phospho-RPA2 (T21) Antibody (1G657)

😃Good
Catalog No. TMAC-03627
Anti-Phospho-RPA2 (T21) Antibody (1G657) is a Rabbit antibody targeting Phospho-RPA2 (T21). Anti-Phospho-RPA2 (T21) Antibody (1G657) can be used in WB,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-RPA2 (T21) Antibody (1G657) is a Rabbit antibody targeting Phospho-RPA2 (T21). Anti-Phospho-RPA2 (T21) Antibody (1G657) can be used in WB,IP.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells, mitochondria, phages and viruses. Replication protein A (RPA), a highly conserved eukaryotic protein, is a heterotrimeric SSB. RPA plays an important role in DNA replication, recombination and repair. The binding of human RPA (hRPA) to DNA involves molecular polarity in which initial hRPA binding occurs on the 5' side of a ssDNA substrate and then extends in the 3' direction to create a stably bound hRPA. RPA is a major damage-recognition protein involved in the early stages of nucleotide excision repair. It can also play a role in telomere maintenance. The C-terminus of RPA 32 can specfically intereact with the DNA repair enzyme UNG2 and repair factors XPA and Rad52, each of which functions in a different repair pathway. In addition, RPA 32 binds specifically to the SH2 domain of Stat3 in vivo, and overexpression of RPA 32 corresponds to the augmented growth factor-stimulated tyrosine phosphorylation and transcription activities of Stat3.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Thr21 of human RPA32/RPA2
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 32 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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