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Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody 2 (Synonyms: p-Androgen receptor (Y363), p-Androgen...)

Catalog No. TMAC-00198 Copy Product Info
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Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Androgen receptor (Tyr363). Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody can be used in WB.

Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody 2

Copy Product Info
🥰Excellent
Catalog No. TMAC-00198
Synonyms p-Androgen receptor (Y363), p-Androgen receptor (Tyr363), Androgen receptor (p-Y363), Androgen receptor (p-Tyr363)

Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Androgen receptor (Tyr363). Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody can be used in WB.

Anti-Phospho-Androgen receptor
(Tyr363) Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2167-10 days7-10 days
100 μL$3177-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Androgen receptor (Tyr363). Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody can be used in WB.
Synonymsp-Androgen receptor (Y363), p-Androgen receptor (Tyr363), Androgen receptor (p-Y363), Androgen receptor (p-Tyr363)
Ig Type
IgG
Reactivity
Human,Mouse
Verified Activity
1. Western blot analysis of extracts from HuvEc cells (Lane 2), COS7 cells (Lane 3) and JK cells (Lane 4), using Androgen Receptor (Phospho-Tyr363) Antibody TMAC-00198. The lane on the left is treated with antigen-specific peptide.
verifiedActivity
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 363 (D-Y-Y(p)-N-F) derived from Human Androgen Receptor
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 85 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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