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Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody 2
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Catalog No. TMAC-00198
Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Androgen receptor (Tyr363). Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody can be used in WB.
Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody 2
Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody 2
😃Good
Catalog No. TMAC-00198
Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Androgen receptor (Tyr363). Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $216 | 7-10 days | |
| 100 μL | $317 | 7-10 days |
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| Description | Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Androgen receptor (Tyr363). Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 363 (D-Y-Y(p)-N-F) derived from Human Androgen Receptor |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 85 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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