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Anti-tPA Antibody (1F455)
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Catalog No. TMAH-00989
Alias t-plasminogen activator, T-PA, TPA, Tissue plasminogen activator
Anti-tPA Antibody (1F455) is an antibody targeting tPA. Anti-tPA Antibody (1F455) can be used in ELISA, FCM.
Anti-tPA Antibody (1F455)
Anti-tPA Antibody (1F455)
😃Good
Catalog No. TMAH-00989Alias t-plasminogen activator, T-PA, TPA, Tissue plasminogen activator
Anti-tPA Antibody (1F455) is an antibody targeting tPA. Anti-tPA Antibody (1F455) can be used in ELISA, FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $207 | 7-10 days | |
| 100 μL | $348 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA, FCM Reactivity: Human |
| Alias | t-plasminogen activator, T-PA, TPA, Tissue plasminogen activator |
| Ig Type | Rabbit IgG |
| Clone | 1F455 |
| Reactivity | Human |
| Verified Activity | Overlay Peak curve showing Hela cells stained with TMAH-00989 (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| Application | ELISA, FCM |
| Recommended Dose | FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Secreted, extracellular space. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human PLAT |
| Antigen Species | Human |
| Gene ID | 5327 |
| Uniprot ID | |
| Biology Area | Cancer, Cardiovascular, Cell biology, Metabolism |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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