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Anti-tPA Antibody (1F455) (Synonyms: t-plasminogen activator, T-PA, TPA, Tissue plasminogen activator)

Catalog No. TMAH-00989 Copy Product Info
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Anti-tPA Antibody (1F455) is an antibody targeting tPA. Anti-tPA Antibody (1F455) can be used in ELISA,FCM.

Anti-tPA Antibody (1F455)

Copy Product Info
🥰Excellent
Catalog No. TMAH-00989
Synonyms t-plasminogen activator, T-PA, TPA, Tissue plasminogen activator

Anti-tPA Antibody (1F455) is an antibody targeting tPA. Anti-tPA Antibody (1F455) can be used in ELISA,FCM.

Anti-tPA Antibody
(1F455)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3487-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-tPA Antibody (1F455) is an antibody targeting tPA. Anti-tPA Antibody (1F455) can be used in ELISA,FCM.
Synonymst-plasminogen activator, T-PA, TPA, Tissue plasminogen activator
Ig Type
Rabbit IgG
Clone
1F455
Reactivity
Human
Verified Activity
Overlay Peak curve showing Hela cells stained with TMAH-00989 (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed.
Application
Recommended Dose
FCM:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationSecreted, extracellular space.
Tissue SpecificitySynthesized in numerous tissues (including tumors) and secreted into most extracellular body fluids, such as plasma, uterine fluid, saliva, gingival crevicular fluid, tears, seminal fluid, and milk.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundConverts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human PLAT
Antigen Species
Human
Gene Name
PLAT
Gene ID
Uniprot ID
Biology Area
Cancer, Cardiovascular, Cell biology, Metabolism
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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