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IL-5 Protein, Mouse, Recombinant (His & Avi)

Catalog No. TMPK-00771
Synonyms: Interleukin-5, EDF, TRF, IL-5, T-cell replacing factor

IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
IL-5 Protein, Mouse, Recombinant (His & Avi)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 418.00
500 μg 5 days $ 1,670.00
1 mg 5 days $ 2,800.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA).
Species Mouse
Expression System HEK293
Tag N-His-Avi
Accession Number P04401
Synonyms Interleukin-5, EDF, TRF, IL-5, T-cell replacing factor
Construction Recombinant Mouse IL-5 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus. It contains Met21-Gly133.[Accession |P04401]
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight The protein has a predicted MW of 16.03 kDa. Due to glycosylation, the protein migrates to 16.03 kDa and 20-32 kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per ug by the LAL method.
Formulation Supplied as 0.22μm filtered solution in 20mM Tris, 500mM NaCl, 10% Glycerol (pH 7.0).
Stability & Storage

Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA).

References and Literature

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Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

IL-5 Protein, Mouse, Recombinant (His & Avi) Interleukin-5 IL 5 EDF TRF IL-5 T-cell replacing factor IL5 recombinant recombinant-proteins proteins protein

 

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