IL-5 Protein, Mouse, Recombinant (His & Avi)

Name: IL-5 Protein, Mouse, Recombinant (His & Avi)
Brand: TargetMol
SKU: TMPK-00771
Rating: 4.5 (1 reviews)

(Synonyms: TRF, T-cell replacing factor, Interleukin-5, IL-5, EDF) Copy Product Info

Synonyms: TRF, T-cell replacing factor, Interleukin-5, IL-5, EDF

Catalog No. TMPK-00771 Copy Product Info

IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA). IL-5 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 16.03 kDa and the accession number is P04401.

IL-5 Protein, Mouse, Recombinant (His & Avi)

Pack Size	Price	USA Stock	Global Stock
10 µg	$80	7-10 days	7-10 days
20 µg	$129	7-10 days	7-10 days
50 µg	$248	7-10 days	7-10 days
100 µg	$418	7-10 days	7-10 days
200 µg	$757	7-10 days	7-10 days
500 µg	$1,670	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Mouse IL-5 R alpha, His Tag immobilized on CM5 Chip can bind Mouse IL-5, His Tag with an affinity constant of 0.495 μM as determined in SPR assay.
Description	IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA). IL-5 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 16.03 kDa and the accession number is P04401.
Species	Mouse
Expression System	HEK293 Cells
Tag	N-His-Avi
Accession Number	P04401
Construction	Met21-Gly133
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl, 10% Glycerol (pH 7.0).
Synonyms	TRF, T-cell replacing factor, Interleukin-5, IL-5, EDF
Research Background	IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA).

Chemical Properties

Molecular Weight

16.03 kDa (predicted). Due to glycosylation, the protein migrates to 16.03 kDa and 20-32 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.