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Glypromate (Synonyms: Gly-Pro-Glu)

Catalog No. T7778 Copy Product Info
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Glypromate (Gly-Pro-Glu) is a neuroprotective agent, is a weak NMDA receptor agonist

Glypromate

Copy Product Info
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Catalog No. T7778
Synonyms Gly-Pro-Glu

Glypromate (Gly-Pro-Glu) is a neuroprotective agent, is a weak NMDA receptor agonist

Glypromate
Cas No. 32302-76-4
Pack SizePriceUSA StockGlobal StockQuantity
5 mg$42In Stock-
10 mg$66In Stock-
25 mg$132In Stock-
50 mg$214In Stock-
100 mg$337In Stock-
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Glypromate (Gly-Pro-Glu) is a neuroprotective agent, is a weak NMDA receptor agonist
In vivo
Glypromate?is neuroprotective after central administration in animal models of neurodegenerative processes, such as Huntington's, Parkinson's, Alzheimer's diseases, and varies acute brain injury animal models.
SynonymsGly-Pro-Glu
Chemical Properties
Molecular Weight301.3
FormulaC12H19N3O6
Cas No.32302-76-4
SmilesC(N[C@@H](CCC(O)=O)C(O)=O)(=O)[C@H]1N(C(CN)=O)CCC1
Relative Density.1.431 g/cm3 (Predicted)
SequenceH-Gly-Pro-Glu-OH
Sequence ShortGPE
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mM, Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3190 mL16.5948 mL33.1895 mL165.9476 mL
5 mM0.6638 mL3.3190 mL6.6379 mL33.1895 mL
10 mM0.3319 mL1.6595 mL3.3190 mL16.5948 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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