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CD20 Protein, Human, Recombinant (His & Avi), Biotinylated
(Synonyms: MS4A-1, MS4A1, Membrane-spanning 4-domains subfamily A member 11, Leukocyte surface antigen Leu-16, CD20, Bp35, B-lymphocyte surface antigen B1) Copy Product InfoSynonyms: MS4A-1, MS4A1, Membrane-spanning 4-domains subfamily A member 11, Leukocyte surface antigen Leu-16, CD20, Bp35, B-lymphocyte surface antigen B1
Catalog No. TMPK-00184 Copy Product Info
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases. CD20 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with C-His-Avi tag. The predicted molecular weight is 16.8 kDa and the accession number is P11836-1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $148 | 7-10 days | 7-10 days | |
| 20 µg | $245 | 7-10 days | 7-10 days | |
| 50 µg | $483 | 7-10 days | 7-10 days | |
| 100 µg | $813 | 7-10 days | 7-10 days | |
| 200 µg | $1,470 | 7-10 days | 7-10 days | |
| 500 µg | $3,250 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Biotinylated Human CD20, His Tag at 1μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Anti-CD20 Antibody, hFc Tag with the EC50 of 87.3ng/ml determined by ELISA. |
| Description | B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases. CD20 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with C-His-Avi tag. The predicted molecular weight is 16.8 kDa and the accession number is P11836-1. |
| Species | Human |
| Expression System | E. coli |
| Tag | C-His-Avi |
| Accession Number | P11836-1 |
| Construction | Ile141-Ser188 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in 20 mM PB , 10% Glycerol (pH 7.0). |
| Synonyms | MS4A-1, MS4A1, Membrane-spanning 4-domains subfamily A member 11, Leukocyte surface antigen Leu-16, CD20, Bp35, B-lymphocyte surface antigen B1 |
| Research Background | B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases. |
| Molecular Weight | 16.8 kDa (predicted) same as Tris-Bis PAGE result. |
| Shipping | Proteins are shipped with blue ice. |
| Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: CD20 Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | CD20 Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight
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