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NKG2D/CD314 Protein, Mouse, Recombinant (aa 87-219, His)
(Synonyms: NKG2-D, Nkg2d, Klrk1, D6H12S2489E) Copy Product InfoSynonyms: NKG2-D, Nkg2d, Klrk1, D6H12S2489E
Catalog No. TMPY-07227 Copy Product Info
NKG2D/CD314 Protein, Mouse, Recombinant (aa 87-219, His) is expressed in Baculovirus-Insect Cells. The accession number is O54709.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $68 | - | In Stock | |
| 10 µg | $109 | - | In Stock | |
| 20 µg | $172 | 7-10 days | 7-10 days | |
| 50 µg | $343 | 7-10 days | 7-10 days | |
| 100 µg | $682 | 7-10 days | 7-10 days | |
| 200 µg | $987 | 7-10 days | 7-10 days | |
| 500 µg | $2,200 | 7-10 days | 7-10 days | |
| 1 mg | $4,500 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:≥ 95 % as determined by SDS-PAGE.
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Recombinant Mouse NKG2D Protein (ECD, His Tag) at 2 μg/mL (100 μL/well) can bind Recombinant Human ULBP1/RAET1/N2DL1 Protein (His & Fc Tag), the EC50 is 8-24 ng/mL. |
| Description | NKG2D/CD314 Protein, Mouse, Recombinant (aa 87-219, His) is expressed in Baculovirus-Insect Cells. The accession number is O54709. |
| Species | Mouse |
| Expression System | Baculovirus Insect Cells |
| Tag | N-His |
| Accession Number | O54709 |
| Construction | A DNA sequence encoding the Mouse KLRK1 (NP_001076791.1) (Asn87-Val219) was expressed, with a polyhistidine tag at the N-terminus. |
| Protein Purity | ≥ 95% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | NKG2-D, Nkg2d, Klrk1, D6H12S2489E |
| Research Background | KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. To transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stimulatory signals to activate CD8 T cells. NKG2D also plays an important role in viral control. Cellular stress can induce ligands for NKG2D which results in the cell susceptible to NK cell-mediated lysis. |
| Molecular Weight | 16.6 kDa (predicted); 24 kDa and 21 kDa (reducing contition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: NKG2D/CD314 Protein, Mouse, Recombinant (aa 87-219, His) chemical structure | NKG2D/CD314 Protein, Mouse, Recombinant (aa 87-219, His) molecular weight
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