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Anti-Lipoprotein lipase Polyclonal Antibody 2

(Synonyms: LPL, Lipoprotein lipase, LIPL, LIPD, HDLCQ11;MGC137861, EC 3.1.1.34) Copy Product Info
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Synonyms: LPL, Lipoprotein lipase, LIPL, LIPD, HDLCQ11;MGC137861, EC 3.1.1.34

Catalog No. TMAB-01074 Copy Product Info
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Anti-Lipoprotein lipase Polyclonal Antibody 2 is a Rabbit antibody targeting Lipoprotein lipase. Anti-Lipoprotein lipase Polyclonal Antibody 2 can be used in FCM,IF,IHC-Fr,IHC-P,WB.
Anti-Lipoprotein lipase Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:/
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Anti-Lipoprotein lipase Polyclonal Antibody 2 is a Rabbit antibody targeting Lipoprotein lipase. Anti-Lipoprotein lipase Polyclonal Antibody 2 can be used in FCM,IF,IHC-Fr,IHC-P,WB.
SynonymsLPL, Lipoprotein lipase, LIPL, LIPD, HDLCQ11;MGC137861, EC 3.1.1.34
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse,Rabbit)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 0.2μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Locates to the plasma membrane of microvilli of hepatocytes with triacyl-glycerol-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles.
Tissue SpecificityDetected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T lymphocytes, neutrophils, monocytes, B lymphocytes, and myeloid cells.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundLipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human LPL protein
Antigen Species
Human
Gene Name
LPL
Gene ID
Protein Name
Lipoprotein lipase
Uniprot ID
Biology Area
Metabolism of lipids and lipoproteins,Lipases,Lipases,Lipid metabolism,Cancer,Obesity,Lipid metabolism,Adipogenesis
Function
Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69.
Chemical Properties
Molecular WeightTheoretical: 53 kDa. Actual: 60 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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