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Anti-CXCR2 Polyclonal Antibody 2

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Catalog No. TMAB-00507

Anti-CXCR2 Polyclonal Antibody 2 is a Rabbit antibody targeting CXCR2. Anti-CXCR2 Polyclonal Antibody 2 can be used in WB.

Anti-CXCR2 Polyclonal Antibody 2

Anti-CXCR2 Polyclonal Antibody 2

😃Good
Catalog No. TMAB-00507
Anti-CXCR2 Polyclonal Antibody 2 is a Rabbit antibody targeting CXCR2. Anti-CXCR2 Polyclonal Antibody 2 can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$222 7-10 days
100 μL$374 7-10 days
200 μL$527 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Polyclonal

Application: WB

Reactivity: Human,Mouse,Rat
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Sample:
Lane 1: Raw264.7 (Mouse) Cell Lysate at 30 μg
Lane 2: U937 (Human) Cell Lysate at 30 μg
Primary: Anti-CXCR2 (TMAB-00507) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45/55 kDa
Observed band size: 59 kDa
2. Sample:
Lane 1: Human THP-1 cell lysates
Lane 2: Human U937 cell lysates
Lane 3: Human HL60 cell lysates
Lane 4: Human HepG2 cell lysates
Primary: Anti-CXCR2 (TMAB-00507) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 41 kDa
Observed band size: 55 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundThe protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CXCR2
Antigen Species
Human
Gene ID
3579
Uniprot ID
Biology Area
GPCR,SARS Coronavirus,Other cell division antibodies
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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