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IL-13 Protein, Human, Recombinant (His & Avi)

(Synonyms: P600, NC30, MGC116789, MGC116788, MGC116786, interleukin 13, IL-13, IL13, BHR1, ALRH) Copy Product Info

Synonyms: P600, NC30, MGC116789, MGC116788, MGC116786, interleukin 13, IL-13, IL13, BHR1, ALRH

Catalog No. TMPK-00617 Copy Product Info
Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity).
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$51-In Stock
10 μg$807-10 days7-10 days
20 μg$1297-10 days7-10 days
50 μg$2487-10 days7-10 days
100 μg$4187-10 days7-10 days
200 μg$7577-10 days7-10 days
500 μg$1,670-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Description
Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity).
Species
Human
Expression System
HEK293 Cells
TagN-His-Avi
Accession NumberAAK53823
ConstructionGly21-Asn132
Protein Purity
> 90% as determined by Tris-Bis PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsP600, NC30, MGC116789, MGC116788, MGC116786, interleukin 13, IL-13, IL13, BHR1, ALRH
Research Background
Chemical Properties
Molecular Weight15.3 kDa (predicted). Due to glycosylation, the protein migrates to 15 kDa and 25-45 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: IL-13 Protein, Human, Recombinant (His & Avi) chemical structure | IL-13 Protein, Human, Recombinant (His & Avi) molecular weight