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RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag)
(Synonyms: TRANCE, TNFSF11, sOdf, RANKL, OPTB2, OPGL, ODF, CD254) Copy Product InfoSynonyms: TRANCE, TNFSF11, sOdf, RANKL, OPTB2, OPGL, ODF, CD254
Catalog No. TMPK-00717 Copy Product Info
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 22.6 kDa and the accession number is O14788-2.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $58 | - | In Stock | |
| 10 μg | $92 | - | In Stock | |
| 20 μg | $148 | - | In Stock | |
| 50 μg | $289 | - | In Stock | |
| 100 μg | $487 | - | In Stock | |
| 200 μg | $883 | 7-10 days | 7-10 days | |
| 500 μg | $1,950 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 90% as determined by Bis-Tris PAGE
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 22.6 kDa and the accession number is O14788-2. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-His-Flag |
| Accession Number | O14788-2 |
| Construction | Gly63-Asp244 |
| Protein Purity | > 90% as determined by Tris-Bis PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | TRANCE, TNFSF11, sOdf, RANKL, OPTB2, OPGL, ODF, CD254 |
| Research Background |
| Molecular Weight | 22.6 kDa (predicted). Due to glycosylation, the protein migrates to 35-60 kDa based on Tris-Bis PAGE result. |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag) chemical structure | RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag) molecular weight
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