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2'-Deoxyuridine 5'-monophosphate disodium (Synonyms: 2'-dUMP⋅2Na, 2'-Deoxyuridine 5'-monophosphate disodium sal...)

Name: 2'-Deoxyuridine 5'-monophosphate disodium
Brand: TargetMol
SKU: T4735
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T4735 Copy Product Info

Purity: 99.18%

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2'-Deoxyuridine 5'-monophosphate disodium (2'-dUMP⋅2Na) salt is utilized by the enzyme thymidylate synthetase (TS) for the de novo synthesis of dTMP and serves as the reference substrate in studies of dUMP analogues for potential chemotherapy applications.

2'-Deoxyuridine 5'-monophosphate disodium

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Catalog No. T4735

Synonyms 2'-dUMP⋅2Na, 2'-Deoxyuridine 5'-monophosphate disodium salt

Cas No. 42155-08-8

Pack Size	Price	USA Stock	Global Stock	Quantity
50 mg	$29	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.18%

Appearance:Solid

Color:White

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	2'-Deoxyuridine 5'-monophosphate disodium (2'-dUMP⋅2Na) salt is utilized by the enzyme thymidylate synthetase (TS) for the de novo synthesis of dTMP and serves as the reference substrate in studies of dUMP analogues for potential chemotherapy applications.
Synonyms	2'-dUMP⋅2Na, 2'-Deoxyuridine 5'-monophosphate disodium salt

Chemical Properties

Molecular Weight	352.15
Formula	C₉H₁₁N₂Na₂O₈P
Cas No.	42155-08-8
Smiles	[Na+].[Na+].O[C@H]1C[C@@H](O[C@@H]1COP([O-])([O-])=O)n1ccc(=O)[nH]c1=O
Relative Density.	1.742 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Slightly soluble

H2O: 520 mg/mL (1476.64 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	2.8397 mL	14.1985 mL	28.3970 mL	141.9849 mL
5 mM	0.5679 mL	2.8397 mL	5.6794 mL	28.3970 mL
10 mM	0.2840 mL	1.4198 mL	2.8397 mL	14.1985 mL
20 mM	0.1420 mL	0.7099 mL	1.4198 mL	7.0992 mL
50 mM	0.0568 mL	0.2840 mL	0.5679 mL	2.8397 mL
100 mM	0.0284 mL	0.1420 mL	0.2840 mL	1.4198 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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