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Anti-Phospho-ATR (Thr1989) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ATR (Thr1989). Anti-Phospho-ATR (Thr1989) Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $218 | 7-10 days | |
100 μL | $316 | 7-10 days |
Description | Anti-Phospho-ATR (Thr1989) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ATR (Thr1989). Anti-Phospho-ATR (Thr1989) Polyclonal Antibody can be used in WB. |
Alias | Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1) |
Ig Type | IgG |
Reactivity | Human |
Application | |
Recommended Dose | WB: 1:1000-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
Appearance | Liquid |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Research Background | ATR serine/threonine kinase(ATR) Homo sapiens The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq, Jul 2008], |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | A synthesized phosphopeptide: human ATR around the phosphorylation site of Thr1989 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Actual: 300 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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