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Methylcarbamyl PAF C-16

Name: Methylcarbamyl PAF C-16
Brand: TargetMol
SKU: T36205
Rating: 4.5 (1 reviews)

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Catalog No. T36205Cas No. 91575-58-5

Alias C-PAF, Carbamyl-PAF

Methylcarbamyl PAF C-16 (Carbamyl-PAF) is a platelet-activating factor analogue with PAF agonist properties, activating inflammation in pregnancy tissues and promoting preterm birth.

Methylcarbamyl PAF C-16

😃Good

Catalog No. T36205Alias C-PAF, Carbamyl-PAFCas No. 91575-58-5

Methylcarbamyl PAF C-16 (Carbamyl-PAF) is a platelet-activating factor analogue with PAF agonist properties, activating inflammation in pregnancy tissues and promoting preterm birth.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$185	35 days	35 days
5 mg	$748	35 days	35 days
10 mg	$1,330	35 days	35 days
25 mg	$2,630	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Appearance:Liquid

Color:Transparent

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COA

Product Introduction

Bioactivity

Description	Methylcarbamyl PAF C-16 (Carbamyl-PAF) is a platelet-activating factor analogue with PAF agonist properties, activating inflammation in pregnancy tissues and promoting preterm birth.
In vitro	Methylcarbamyl PAF C-16 (100 pM-1 μM) increases intracellular free calcium in a dose-dependent manner. Treatment with Methylcarbamyl PAF C-16 (10 pM-1 μM) did not affect the spontaneous proliferation of Raji lymphocytes. [1]
Synonyms	C-PAF, Carbamyl-PAF

Chemical Properties

Molecular Weight	538.7
Formula	C₂₆H₅₅N₂O₇P
Cas No.	91575-58-5
Smiles	[C@H](COP(OCC[N+](C)(C)C)(=O)[O-])(COCCCCCCCCCCCCCCCC)OC(NC)=O

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMF: 10 mg/mL (18.56 mM), Sonication is recommended.

Ethanol: 20 mg/mL (37.13 mM), Sonication is recommended.

DMSO: 10 mg/mL (18.56 mM), Sonication is recommended.

PBS (pH 7.2): 10 mg/mL (18.56 mM), Sonication is recommended.

Solution Preparation Table

DMF/DMSO/PBS (pH 7.2)/Ethanol

	1mg	5mg	10mg	50mg
1 mM	1.8563 mL	9.2816 mL	18.5632 mL	92.8160 mL
5 mM	0.3713 mL	1.8563 mL	3.7126 mL	18.5632 mL
10 mM	0.1856 mL	0.9282 mL	1.8563 mL	9.2816 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc