Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH. It is nearly equipotent with PAF C-16 in its ability to induce platelet aggregation both in isolated platelets and in platelet-rich plasma. In NRK-49 cells overexpressing the PAF receptor, both PAF C-16 and methylcarbamyl PAF C-16 cause the induction of c-myc and c-fos and the activation of mitogen-activated protein kinase. Methylcarbamyl PAF C-16 induces G1 phase cell cycle arrest, suggesting a potential role for PAF in the inhibition of oncogenic transformation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 88.00 | |
5 mg | 35 days | $ 388.00 | |
10 mg | 35 days | $ 688.00 | |
25 mg | 35 days | $ 1,360.00 |
Description | Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH. It is nearly equipotent with PAF C-16 in its ability to induce platelet aggregation both in isolated platelets and in platelet-rich plasma. In NRK-49 cells overexpressing the PAF receptor, both PAF C-16 and methylcarbamyl PAF C-16 cause the induction of c-myc and c-fos and the activation of mitogen-activated protein kinase. Methylcarbamyl PAF C-16 induces G1 phase cell cycle arrest, suggesting a potential role for PAF in the inhibition of oncogenic transformation. |
Molecular Weight | 538.7 |
Formula | C26H55N2O7P |
CAS No. | 91575-58-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: >25 mg/mL
Ethanol: >50 mg/mL
DMSO: >25 mg/mL
PBS (pH 7.2): >25 mg/mL
You can also refer to dose conversion for different animals. More
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Methylcarbamyl PAF C-16 91575-58-5 Methylcarbamyl PAF C 16 Methylcarbamyl PAF C16 inhibitor inhibit